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放射学检查无异常的缩乳标本。我们是否仍应将其送检病理实验室?

Radiologically innocuous breast reduction specimens. Should we send them to pathology lab anyway?

作者信息

Celik B, Senen Demiroz D, Yaz M, Muslu U

出版信息

G Chir. 2013 Nov-Dec;34(11-12):302-6.

PMID:24342155
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3926466/
Abstract

Breast Reduction (BR) is a common procedure around the world. Patients are screened for incidental carcinoma preoperatively by mammography or ultrasonography and BR specimens are sent for pathologic examination postoperatively. Since the incidence of incidental carcinoma is very low, no consensus exist regarding efficiency of pathologic examination. To assess the value of pathologic examination, we examined mammographically and ultrasonographically negative eighty BR specimens from 40 women. Twenty seven women had pathological lesions in their specimens (67,5%). This indicates that, even mammographically and ultrasonographically innocuous, BR specimens may reveal important pathological diagnosis that alters patient management.

摘要

乳房缩小术(BR)在全球都是一种常见的手术。术前通过乳房X线摄影或超声对患者进行偶然癌筛查,术后将BR标本送去做病理检查。由于偶然癌的发生率非常低,关于病理检查的效率尚无共识。为了评估病理检查的价值,我们检查了40名女性的80份经乳房X线摄影和超声检查均为阴性的BR标本。27名女性的标本中有病理病变(67.5%)。这表明,即使经乳房X线摄影和超声检查无异常,BR标本也可能揭示重要的病理诊断结果,从而改变患者的治疗方案。

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本文引用的文献

1
Should we be analysing breast reduction specimens? A systematic analysis of over 1,000 consecutive cases.我们是否应该分析乳房缩小标本?对 1000 多例连续病例的系统分析。
Aesthetic Plast Surg. 2012 Oct;36(5):1105-13. doi: 10.1007/s00266-012-9919-9. Epub 2012 Jun 8.
2
Radiotherapy after conservative surgery in ductal carcinoma in situ of the breast: a review.乳腺导管原位癌保乳手术后的放射治疗:综述
Int J Surg Oncol. 2012;2012:635404. doi: 10.1155/2012/635404. Epub 2012 May 13.
3
The incidence of non-proliferative and precancerous lesions of reduction mammoplasty: evaluation of 273 cases.缩乳术中非增生性和癌前病变的发生率:273 例评估。
Eur Rev Med Pharmacol Sci. 2011 Oct;15(10):1207-11.
4
Oncological screening for Bilateral Breast Reduction: a survey of practice variations in UK Breast and Plastics surgeons 2009.2009 年英国乳腺与整形外科医师对双侧乳房缩小术的肿瘤学筛查:实践差异的调查
J Plast Reconstr Aesthet Surg. 2011 Jul;64(7):878-83. doi: 10.1016/j.bjps.2010.12.001. Epub 2010 Dec 31.
5
The price of pathology: is screening all breast reduction specimens cost effective?
Plast Reconstr Surg. 2010 May;125(5):1575-1576. doi: 10.1097/PRS.0b013e3181d5139e.
6
Incidence of precancerous lesions in breast reduction tissue: a pathologic review of 562 consecutive patients.缩乳组织中癌前病变的发生率:对562例连续患者的病理回顾
Plast Reconstr Surg. 2009 Oct;124(4):1033-1039. doi: 10.1097/PRS.0b013e3181b45801.
7
Frequency of clinically occult intraepithelial and invasive neoplasia in reduction mammoplasty specimens: a study of 516 cases.缩乳术标本中临床隐匿性上皮内瘤变和浸润性肿瘤的发生率:一项516例病例的研究
Int J Surg Pathol. 2008 Jan;16(1):25-30. doi: 10.1177/1066896907307176.
8
Histopathological findings in surgical specimens obtained from reduction mammaplasties.从缩乳术中获取的手术标本的组织病理学发现。
Breast. 2005 Jun;14(3):242-8. doi: 10.1016/j.breast.2004.12.006.
9
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Plast Reconstr Surg. 2004 Jun;113(7):1984-8. doi: 10.1097/01.prs.0000122212.37703.6e.
10
Does histopathological examination of breast reduction specimens affect patient management and clinical follow up?对缩乳标本进行组织病理学检查会影响患者的治疗管理和临床随访吗?
J Clin Pathol. 2004 Mar;57(3):286-9. doi: 10.1136/jcp.2003.012427.