Głyda Maciej, Czapiewski Wojciech, Karczewski Marek, Pięta Renata, Oko Andrzej
Department of Transplantology and Surgery, Provincial Hospital in Poznań.
Pol Przegl Chir. 2011 Apr;83(4):188-95. doi: 10.2478/v10035-011-0029-1.
The aim of the study was to determine the impact of the gender of renal allograft donor and recipient on the graft function over a 5-year follow-up period.
The 154 kidney grafts from 77 donors transplanted into recipients of both genders. Two study groups were formed: one group consisted of male donors, while the other consisted of female donors. The recipients in each of the groups consisted of a pair, one male and one female.
71% of grafts survived the five-year period in the group of male and female recipients when the donor was male; in case of female donors, the rate was 62.5%. Depending on the gender of the donor and the recipient, the rates of grafts with five-year survival were as follows: 79.2% for male donors and female recipients (MF); 62.5% for male donors and male recipients (MM). The difference between both groups was not statistically significant. In the case of female donors and male recipients (FM), the five-year survival rate was 58.3%, while in female donors and female recipients, the five-year survival rate was 64.1%.
Grafts from male donors show a trend towards better five-year survival compared to grafts from female donors. The highest five-year survival rate was observed when the donor was male and the recipient was female; the lowest rate was observed for female donors and male recipients.
本研究的目的是确定在5年的随访期内，肾移植供体和受体的性别对移植肾功能的影响。
将来自77名供体的154个肾移植给不同性别的受体。形成了两个研究组：一组由男性供体组成，另一组由女性供体组成。每组中的受体由一对组成，一男一女。
当供体为男性时，男性和女性受体组中71%的移植物存活了5年；在女性供体的情况下，这一比例为62.5%。根据供体和受体的性别，5年存活移植物的比例如下：男性供体和女性受体（MF）为79.2%；男性供体和男性受体（MM）为62.5%。两组之间的差异无统计学意义。在女性供体和男性受体（FM）的情况下，5年生存率为58.3%，而在女性供体和女性受体的情况下，5年生存率为64.1%。
与女性供体的移植物相比，男性供体的移植物显示出5年生存率更高的趋势。当供体为男性而受体为女性时，观察到最高的5年生存率；女性供体和男性受体的生存率最低。
