Suppr超能文献

无症状性颅外动脉粥样硬化性颈动脉疾病的诊断与治疗

[Diagnosis and treatment of asymptomatic extracranial atherosclerotic carotid artery disease].

作者信息

Sposato Luciano A, Riccio Patricia M, Klein Francisco R

机构信息

Departamento de Neurología, INECO e Instituto de Investigación Neurovascular, Fundación INECO, Buenos Aires.

出版信息

Medicina (B Aires). 2011;71(6):561-5.

Abstract

The reported prevalence of asymptomatic atherosclerotic disease of the extracranial internal carotid artery is up to 12.5%. Carotid angioplasty has not yet proven safe and effective enough to prevent ischemic stroke in these patients. Randomized studies showed that carotid endarterectomy is superior to medical therapy in reducing the risk of ischemic stroke when performed by surgical teams with complication rates (stroke or death) of less than 3%. However, recruitment of these patients began more than 25 years ago, when the use of antiplatelet agents was lower than today, the treatment of hypertension was less effective than currently, and statins were not considered as key components of vascular prevention strategies. Optimizing the quality of medical treatment in recent decades has led to a significant reduction in stroke risk in patients not undergoing surgery. Based on these observations and with the exception of specific cases, medical therapy is the treatment of choice for patients with asymptomatic atherosclerotic disease of the extracranial carotid arteries.

摘要

据报道,颅外颈内动脉无症状性动脉粥样硬化疾病的患病率高达12.5%。对于这些患者,颈动脉血管成形术尚未被证明足够安全有效以预防缺血性卒中。随机研究表明,当由并发症发生率(卒中或死亡)低于3%的手术团队进行颈动脉内膜切除术时,在降低缺血性卒中风险方面优于药物治疗。然而,这些患者的招募始于25年多以前,当时抗血小板药物的使用比现在少,高血压的治疗效果不如目前,并且他汀类药物尚未被视为血管预防策略的关键组成部分。近几十年来医疗质量的优化已导致未接受手术的患者卒中风险显著降低。基于这些观察结果,除特定情况外,药物治疗是颅外颈动脉无症状性动脉粥样硬化疾病患者的首选治疗方法。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验