Labib S, Berdai M-A, Bendadi A, Achour S, Harandou M
Service d'anesthésie réanimation, hôpital mère et enfant, CHU Hassan II de Fès, Fès, Maroc.
Arch Pediatr. 2012 Jan;19(1):59-61. doi: 10.1016/j.arcped.2011.10.011. Epub 2011 Dec 12.
Indigo, also known in Morocco as Nila, is a dye widely used in the coloring of Moroccan handicrafts. It is obtained from fermentation reactions on the leaves and branches of true indigo, Indigofera tinctoria, which is a widespread plant in tropical Africa and Asia. We report a case of fatal poisoning in a 3-year-old child after administration of indigo for therapeutic purposes. Death resulted from multiple organ failure. The toxicity of this compound is little known in the literature and deserves to be explored through toxicokinetic and toxicodynamic studies, in order to better determine the toxic constituents of the dye.
靛蓝，在摩洛哥也被称为尼拉，是一种广泛用于摩洛哥手工艺品染色的染料。它是通过对真靛蓝（Indigofera tinctoria）的叶子和树枝进行发酵反应而获得的，真靛蓝是一种在热带非洲和亚洲广泛分布的植物。我们报告了一例3岁儿童在接受用于治疗目的的靛蓝后发生致命中毒的病例。死亡原因是多器官衰竭。该化合物的毒性在文献中鲜为人知，值得通过毒代动力学和毒效动力学研究进行探索，以便更好地确定该染料的有毒成分。
