Johannes Gutenberg-University Mainz, Institute of Anthropology, Germany.
Ann Anat. 2012 Jan 20;194(1):121-32. doi: 10.1016/j.aanat.2011.11.002. Epub 2011 Nov 18.
The contribution of palaeogenetic data to the study of various aspects of hominin biology and evolution has been significant, and has the potential to increase substantially with the widespread implementation of next generation sequencing techniques. Here we discuss the present state-of-the-art of ancient human DNA analysis and the characteristics of hominin aDNA that make sequence validation particularly complex. A brief overview of the development of anthropological palaeogenetic analysis is given to illustrate the technical challenges motivating recent technological advancements.
古遗传学数据对研究人类生物学和进化的各个方面做出了重要贡献，随着下一代测序技术的广泛应用，其潜在价值将大大增加。在这里，我们讨论了古人类 DNA 分析的现状以及使序列验证特别复杂的人类 DNA 的特征。简要概述了人类学古遗传学分析的发展，以说明推动最近技术进步的技术挑战。
