Mali Ravindra G, Dhake Avinash S
Department of Pharmacognosy, L. B. Rao Institute of Pharmaceutical Education and Research, Shri B. D. Rao College Campus, Khambhat, Gujarat, India.
J Adv Pharm Technol Res. 2011 Apr;2(2):132-4. doi: 10.4103/2231-4040.82949.
Bauhinia variegata Linn (family: Caesalpiniaceae), popularly known as Rakta Kanchnar, is a medium-sized tree found throughout India. The stem bark of B. variegata (BV) is used traditionally in the treatment of asthma, jaundice, tuberculosis, leprosy, and skin diseases. In the present study, we have investigated the role of aqueous (BVA) and ethanol (BVE) extracts of the plant against milk-induced leukocytosis and eosinophilia in albino mice. The results of the study revealed that pretreatment with both the extracts caused significant reduction in the total leukocyte and eosinophil counts in animals in dose-dependent manner. From these results, it can be concluded that the plant BV is having antieosinophilic activity.
洋紫荆(豆科),俗称Rakta Kanchnar,是一种遍布印度的中型树木。洋紫荆(BV)的茎皮传统上用于治疗哮喘、黄疸、肺结核、麻风病和皮肤病。在本研究中,我们研究了该植物的水提取物(BVA)和乙醇提取物(BVE)对白化病小鼠牛奶诱导的白细胞增多和嗜酸性粒细胞增多的作用。研究结果表明,两种提取物预处理均能使动物的总白细胞和嗜酸性粒细胞计数显著降低,且呈剂量依赖性。从这些结果可以得出结论,植物BV具有抗嗜酸性粒细胞活性。