Irish Meningococcal and Meningitis Reference Laboratory (IMMRL), The Children's University Hospital, Dublin, Ireland.
Pediatr Infect Dis J. 2012 Mar;31(3):316-8. doi: 10.1097/INF.0b013e318241f824.
Laboratory methods of diagnosis were examined for 266 children with invasive meningococcal disease. Seventy-five (36%) of 207 cases with bloodstream infection had both positive blood culture and blood meningococcal polymerase chain reaction (PCR), 130 (63%) negative blood culture and positive blood PCR, and 2 (1%) had positive blood culture and negative blood PCR. Sixty-three percent of cases were diagnosed by PCR alone.
对 266 例侵袭性脑膜炎球菌病患儿进行了实验室诊断方法检查。207 例菌血症病例中，75 例（36%）血培养和血液脑膜炎球菌聚合酶链反应（PCR）均为阳性，130 例（63%）血培养阴性但血 PCR 阳性，2 例（1%）血培养阳性但血 PCR 阴性。单纯 PCR 诊断的病例占 63%。
