Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.
Urology. 2012 Mar;79(3):513-7. doi: 10.1016/j.urology.2011.10.017. Epub 2011 Dec 14.
To conduct a comparison of physical and mechanical properties for 5 commonly used guidewires to assess advantages of wires for specific applications.
Tests on guidewires (0.035" diameter; straight, flexible tip) included tip bending, shaft buckling, lubricity, and tip puncture measurements. Guidewires included 2 hybrid wires: the U-Nite (Bard Urological, Covington, GA) and the Sensor (Boston Scientific, Natick, MA). Our aim was to compare the stiffness of these hybrid wires with the standard Amplatz SuperStiff (Boston Scientific). Our second aim was to compare the hydrophilic tip of the hybrid wires with 2 traditional hydrophilic guidewires: the NiCore (Bard Urological) and RadiFocus glidewire (Boston Scientific).
The Amplatz SuperStiff had a significantly stiffer shaft than either hybrid wire, with a buckling force of 1.81 ± 0.91 N compared with the Sensor (0.80 ± 0.29 N, P = .0002) and the U-Nite (0.77 ± 0.29 N, P < .0001). The Boston Scientific guidewire tips were less stiff than the Bard guidewires, requiring up to 48% less force to bend when encountering resistance (P < .0001). The U-Nite had the highest lubricity (0.09 ± 0.03 N, P < .0001) and roundest tip of all the guidewires tested. The RadiFocus required the greatest puncture force (1.80 ± 0.27 N, P < .0001) of all the guidewires tested.
Hybrid wires offer a combination of a stiffer shaft and hydrophilic tip. The Amplatz SuperStiff remains the stiffest wire and as such is best suited for placement of ureteral access sheaths or larger stents. The Boston Scientific wires require less force to "bend" around a point of obstruction compared with the Bard wires. The Boston Scientific RadiFocus requires the greatest force to puncture aluminum foil.
比较 5 种常用导丝的物理和机械性能，评估特定应用中导丝的优势。
对导丝（直径 0.035"；直型、柔性尖端）进行尖端弯曲、轴弯曲、润滑性和尖端刺穿测量。导丝包括 2 种混合导丝：U-Nite（Bard Urological，Covington，GA）和 Sensor（Boston Scientific，Natick，MA）。我们的目的是比较这些混合导丝的刚性与标准的 Amplatz SuperStiff（Boston Scientific）。我们的第二个目的是比较混合导丝的亲水尖端与 2 种传统亲水导丝：NiCore（Bard Urological）和 RadiFocus glidewire（Boston Scientific）。
Amplatz SuperStiff 的轴明显比任何混合导丝都硬，弯曲力为 1.81±0.91 N，与 Sensor（0.80±0.29 N，P=0.0002）和 U-Nite（0.77±0.29 N，P<0.0001）相比。Boston Scientific 导丝的尖端比 Bard 导丝软，遇到阻力时需要的弯曲力小 48%（P<0.0001）。U-Nite 的润滑性最高（0.09±0.03 N，P<0.0001），并且是所有测试导丝中尖端最圆的。所有测试导丝中，RadiFocus 需要的刺穿力最大（1.80±0.27 N，P<0.0001）。
混合导丝具有更硬的轴和亲水尖端的组合。Amplatz SuperStiff 仍然是最硬的导丝，因此最适合放置输尿管接入鞘或更大的支架。与 Bard 导丝相比，Boston Scientific 导丝在绕过障碍物时需要的力更小。Boston Scientific RadiFocus 刺穿铝箔所需的力最大。
