Children's Hospital of Philadelphia Research Institute.
Blood. 2011 Dec 15;118(25):6475-6. doi: 10.1182/blood-2011-10-381392.
In this issue of Blood, Barreira da Silva and colleagues further unravel the mysterious interaction between human NKcells and dendritic cells (DCs) through detailed study of their synaptic interface.1 Here, actin integrity in the DCs works to restrain cytolysis and enable civil cross-talk thus defining a regulatory NK-cell synapse.
在本期《Blood》中，Barreira da Silva 及其同事通过详细研究 NK 细胞和树突状细胞 (DC) 的突触界面，进一步揭示了人类 NK 细胞和 DC 之间神秘的相互作用。1 在这里，DC 中的肌动蛋白完整性有助于抑制细胞溶解并实现细胞间的文明对话，从而定义了一个调节性 NK 细胞突触。
