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欧洲脑部疾病的经济负担。

The economic cost of brain disorders in Europe.

机构信息

Department of Neurology, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark.

出版信息

Eur J Neurol. 2012 Jan;19(1):155-62. doi: 10.1111/j.1468-1331.2011.03590.x.

Abstract

BACKGROUND AND PURPOSE

In 2005, we presented for the first time overall estimates of annual costs for brain disorders (mental and neurologic disorders) in Europe. This new report presents updated, more accurate, and comprehensive 2010 estimates for 30 European countries.

METHODS

One-year prevalence and annual cost per person of 19 major groups of disorders are based on 'best estimates' derived from systematic literature reviews by panels of experts in epidemiology and health economics. Our cost estimation model was populated with national statistics from Eurostat to adjust to 2010 values, converting all local currencies to Euros (€), imputing cost for countries where no data were available, and aggregating country estimates to purchasing power parity-adjusted estimates of the total cost of brain disorders in Europe in 2010.

RESULTS

Total European 2010 cost of brain disorders was €798 billion, of which direct health care cost 37%, direct non-medical cost 23%, and indirect cost 40%. Average cost per inhabitant was €5.550. The European average cost per person with a disorder of the brain ranged between €285 for headache and €30 000 for neuromuscular disorders. Total annual cost per disorder (in billion € 2010) was as follows: addiction 65.7; anxiety disorders 74.4; brain tumor 5.2; child/adolescent disorders 21.3; dementia 105.2; eating disorders 0.8; epilepsy 13.8; headache 43.5; mental retardation 43.3; mood disorders 113.4; multiple sclerosis 14.6; neuromuscular disorders 7.7; Parkinson's disease 13.9; personality disorders 27.3; psychotic disorders 93.9; sleep disorders 35.4; somatoform disorder 21.2; stroke 64.1; and traumatic brain injury 33.0.

CONCLUSION

Our cost model revealed that brain disorders overall are much more costly than previously estimated constituting a major health economic challenge for Europe. Our estimate should be regarded as conservative because many disorders or cost items could not be included because of lack of data.

摘要

背景与目的

2005 年,我们首次提出了欧洲脑疾病(精神和神经疾病)的年度费用的总体估计。本报告提供了更新、更准确和全面的 2010 年欧洲 30 个国家的估计。

方法

19 大组疾病的一年患病率和每人每年成本是基于专家小组通过系统文献综述得出的“最佳估计数”。我们的成本估算模型使用了来自 Eurostat 的国家统计数据进行调整,以适应 2010 年的数据,将所有本国货币转换为欧元(€),对没有数据的国家进行成本估算,以及将各国的估算汇总为欧洲 2010 年脑疾病的购买力平价调整后的总成本的估算。

结果

2010 年欧洲脑疾病总成本为 7980 亿欧元,其中直接医疗费用占 37%,直接非医疗费用占 23%,间接费用占 40%。人均平均成本为 5550 欧元。欧洲每例脑疾病患者的平均费用在 285 欧元(头痛)至 30000 欧元(神经肌肉疾病)之间不等。2010 年每例疾病的年总成本(以十亿欧元计)如下:成瘾 657;焦虑症 744;脑瘤 52;儿童/青少年障碍 213;痴呆症 1052;饮食障碍 08;癫痫 138;头痛 435;智力迟钝 433;情绪障碍 1134;多发性硬化症 146;神经肌肉疾病 77;帕金森病 139;人格障碍 273;精神病障碍 939;睡眠障碍 354;躯体形式障碍 212;中风 641;创伤性脑损伤 330。

结论

我们的成本模型显示,脑疾病的总成本远高于之前的估计,这对欧洲的卫生经济构成了重大挑战。由于缺乏数据,许多疾病或成本项目无法包括在内,因此我们的估计应被视为保守估计。

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