Bisdorff A, Sobocki P, Cloos J M, Andrée C, Graziano M E
Department of Neurology, Centre Hospitalier Emile Mayrisch, Esch-sur-Alzette, Luxembourg.
Bull Soc Sci Med Grand Duche Luxemb. 2006(3):347-58.
Brain disorders (psychiatric, neurological and neurosurgical diseases) are leading causes of disease and disability. According to WHO data they cause 35% of the burden of all diseases in Europe. The present study aims to estimate the cost of defined brain disorders and adds all selected disorders to arrive at the total cost for Luxembourg. A model combining published economic and epidemiological data retrieved from the OECD (Organization for Economic Co-operation and Development) and Eurostat databases on brain disorders in Europe (EU member countries, Iceland, Norway and Switzerland) was used. We transformed and converted data for a defined period into the same currency (Euro 2004) and adjusted country specific economic data for purchasing power and relative size of economy and imputed data where no local data were available. There are an estimated 123000 people in Luxembourg currently living with a brain disorder. The total annual cost of brain disorders is estimated at Euro 500 million in 2004 or an average of Euro 1100 per inhabitant. Mental disorders constitute 62% of the total cost (excluding dementia), followed by neurological diseases (excluding dementia) 22%, neurosurgical diseases excluding herniated discs 2.2%. Direct medical expenditures (outpatient care, hospitalization, drugs) have a share of 32%, direct non-medical costs (social services, informal care, adaptation, transportation) 18% and indirect costs (sick leave, early retirement and premature death) 51%.
脑部疾病（精神疾病、神经疾病和神经外科疾病）是导致疾病和残疾的主要原因。根据世界卫生组织的数据，它们在欧洲造成了所有疾病负担的35%。本研究旨在估算特定脑部疾病的成本，并将所有选定的疾病纳入计算，以得出卢森堡的总成本。我们使用了一个模型，该模型结合了从经合组织（经济合作与发展组织）和欧盟统计局数据库中检索到的关于欧洲（欧盟成员国、冰岛、挪威和瑞士）脑部疾病的已发表经济和流行病学数据。我们将特定时期的数据转换为同一种货币（2004年欧元），并针对购买力、经济相对规模对各国特定经济数据进行了调整，在没有本地数据的情况下进行了数据估算。据估计，卢森堡目前有123000人患有脑部疾病。2004年脑部疾病的年度总成本估计为5亿欧元，即人均1100欧元。精神疾病占总成本的62%（不包括痴呆症），其次是神经疾病（不包括痴呆症）占22%，不包括椎间盘突出症的神经外科疾病占2.2%。直接医疗支出（门诊护理、住院治疗、药品）占32%，直接非医疗成本（社会服务、非正式护理、适应性调整、交通）占18%，间接成本（病假、提前退休和过早死亡）占51%。
