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[在使用乙酰甲胆碱的非特异性支气管激发试验中,使用Astograph同时记录肺量计参数和总呼吸阻力]

[Simultaneous recording of spirometric parameters and total respiratory resistance on the Astograph in nonspecific bronchial provocation tests using methacholine].

作者信息

Balaban J, Tanurdzić S, Durić V, Dimcić Z, Tomasević L

机构信息

Klinika za alergologiju i imunologiju, Univerzitetskog klinickog centra, Beograd.

出版信息

Plucne Bolesti. 1990 Jan-Jun;42(1-2):55-6.

PMID:2217636
Abstract

Parallel study results of spirometric parameters (S.P.) FEV1, FEF50, FEF25 and total respiratory resistance (Rrs) measured by Astograph in nonspecific metacholine bronchoprovocation test were analyzed in 378 patients suspected of bronchial asthma. The patients were divided into 7 groups based on Astograph and S.P. instances criteria. Of 92 patients with positive test results, 91% met the set Astograph criterium; 72% met all three S.P. criteria, 1% one criterium and 12% failed to meet any of the S.P. criteria. It was noted that the patients met more the FEF50 and FEF25 criteria (87%) than FEV1 (73%). Also, there was no significant increase in respiratory resistance for those with a predominant reaction in small airways (9%). This fact points to the need of introducing appropriate complementary Astograph methods.

摘要

对378例疑似支气管哮喘患者在非特异性乙酰甲胆碱支气管激发试验中通过Astograph测量的肺量计参数(S.P.)FEV1、FEF50、FEF25和总呼吸阻力(Rrs)的平行研究结果进行了分析。根据Astograph和S.P.实例标准将患者分为7组。在92例检测结果呈阳性的患者中,91%符合设定的Astograph标准;72%符合所有三项S.P.标准,1%符合一项标准,12%不符合任何一项S.P.标准。值得注意的是,患者符合FEF50和FEF25标准(87%)的比例高于FEV1(73%)。此外,小气道反应为主的患者呼吸阻力无显著增加(9%)。这一事实表明需要引入适当的Astograph补充方法。

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