IBMB (CSIC) and IRB Barcelona, Barcelona, Spain.
Dev Biol. 2012 Feb 15;362(2):187-93. doi: 10.1016/j.ydbio.2011.11.018. Epub 2011 Dec 6.
Connection of epithelial tubes to generate a common network is a key step in the formation of tubular organs such as the tracheal respiratory and the vascular systems. However, it is not clear how these connecting tubes arise. Here we address this issue by studying the dorsal fusion branches in the Drosophila trachea, taking into account the morphology and contribution of each cell type on the basis of their individual labeling. Our results explain how a fusion branch forms and also illustrate the different nature of the two seamless tubes in the Drosophila trachea, generated by fusion and terminal cells respectively.
上皮管的连接是形成管状器官（如气管呼吸和血管系统）的关键步骤。然而，目前尚不清楚这些连接管是如何产生的。在这里，我们通过研究果蝇气管中的背融合分支来解决这个问题，考虑到每个细胞类型的形态和贡献，基于它们的单独标记。我们的结果解释了融合分支是如何形成的，同时也说明了果蝇气管中由融合和终端细胞分别产生的两个无缝管的不同性质。
