Vascular Surgery Research Group, Imperial College at Charing Cross, St Dunstan's Road, London W6 8RP, UK.
Eur J Vasc Endovasc Surg. 2012 Feb;43(2):161-6. doi: 10.1016/j.ejvs.2011.11.014. Epub 2011 Dec 16.
Between 1951 and 1995 there was a steady increase in age-standardised deaths from all aortic aneurysms in men, from 2 to 56 per 100,000 population in England & Wales, supporting an increase in incidence. More recently, evidence from Sweden and elsewhere suggests that now the incidence of abdominal aortic aneurysm (AAA) may be declining.
National statistics for hospital admissions and deaths from AAA, after population age-standardisation, were used to investigate current trends in England & Wales and Scotland.
Between 1997 and 2009 there has been a reduction in age-adjusted mortality from AAA from 40.4 to 25.7 per 100,000 population for England & Wales and from 30.1 to 20.8 per 100,000 population in Scotland. The decrease in mortality was more marked for men than women. Mortality decreased more than 2-fold in those <75 years versus 25% only in those >75 years. During this same time period the elective hospital admissions for AAA repair have only increased in the population >75 years.
These data suggest that the age at which clinically-relevant aneurysms present has increased by 5-10 years and that incidence of clinically-relevant AAA in men in England & Wales and Scotland is declining rapidly. The reasons for this are unclear.
1951 年至 1995 年间，英格兰和威尔士男性所有主动脉瘤的年龄标准化死亡率稳步上升，从每 10 万人 2 例上升至 56 例，提示发病率上升。最近，来自瑞典和其他地区的证据表明，腹主动脉瘤（AAA）的发病率现在可能正在下降。
使用人口年龄标准化后的医院收治 AAA 患者和 AAA 死亡人数的国家统计数据，调查英格兰和威尔士以及苏格兰的当前趋势。
1997 年至 2009 年间，英格兰和威尔士的 AAA 年龄调整死亡率从每 10 万人 40.4 例降至 25.7 例，苏格兰从每 10 万人 30.1 例降至 20.8 例。男性的死亡率下降幅度大于女性。<75 岁人群的死亡率下降超过 2 倍，而>75 岁人群的死亡率仅下降 25%。在此期间，AAA 修复的择期住院治疗仅在>75 岁人群中增加。
这些数据表明，临床上有意义的动脉瘤出现的年龄增加了 5-10 岁，英格兰和威尔士以及苏格兰男性的临床上有意义的 AAA 发病率正在迅速下降。原因尚不清楚。
