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腹主动脉瘤与PET/CT:从分子机制到潜在的分子成像靶点

Abdominal Aortic Aneurysm and PET/CT: From Molecular Mechanisms to Potential Molecular Imaging Targets.

作者信息

Li Chenhao, Liu Zhiyin, Yuan Gang, Liu Yong, Wang Weiming

机构信息

Department of General Surgery (Vascular Surgery), The Affiliated Hospital of Southwest Medical University, 646000 Luzhou, Sichuan, China.

Department of Neurology, The Affiliated Hospital of Southwest Medical University, 646000 Luzhou, Sichuan, China.

出版信息

Rev Cardiovasc Med. 2023 Apr 27;24(5):132. doi: 10.31083/j.rcm2405132. eCollection 2023 May.

Abstract

Abdominal aortic aneurysm (AAA) is the most common and critical aortic disease. Bleeding is the most serious complication from a ruptured AAA, which often results in death. Therefore, early diagnosis and treatment are the only effective means to reduce AAA associated mortality. Positron emission tomography/computed tomography (PET/CT) combines functional and anatomical imaging. The expanded application of PET/CT in the medical field could have benefits for the diagnosis and treatment of patients with AAA. This review explores the efficiency of PET/CT in the diagnosis of AAA based on our understanding of the underlying molecular mechanisms of AAA development.

摘要

腹主动脉瘤(AAA)是最常见且严重的主动脉疾病。出血是AAA破裂最严重的并发症,常导致死亡。因此,早期诊断和治疗是降低AAA相关死亡率的唯一有效手段。正电子发射断层扫描/计算机断层扫描(PET/CT)结合了功能成像和解剖成像。PET/CT在医学领域的广泛应用可能对AAA患者的诊断和治疗有益。本综述基于我们对AAA发生潜在分子机制的理解,探讨PET/CT在AAA诊断中的效能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c05/11273052/e244bf95f47d/2153-8174-24-5-132-g1.jpg

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