Filipovic M, Seagroatt V, Goldacre M J
Unit of Health Care Epidemiology, Department of Public Health, University of Oxford, Oxford, UK.
Br J Surg. 2007 Sep;94(9):1096-9. doi: 10.1002/bjs.5784.
Differences between women and men in treatment and outcome after admission with a ruptured abdominal aortic aneurysm (AAA) in England were studied.
Routinely collected data in Hospital Episode Statistics, linked to death records, for emergency admissions for ruptured AAA in England were analysed. The percentage of patients who underwent surgical repair was calculated, together with 30-day case fatality rates and age-adjusted odds ratios (ORs), comparing women with men.
A total of 2463 women and 7615 men were admitted with a primary diagnosis of ruptured AAA (mean age 79.8 and 74.9 years respectively); 39.6 per cent of women and 66.4 per cent of men underwent surgical repair (OR 0.47 (95 per cent confidence interval 0.42 to 0.52)). Overall, 75.6 per cent of women and 61.7 per cent of men died within 30 days of admission (OR 1.36 (1.22 to 1.52)). The death rate for women and men who had surgery was similar (OR 1.01 (0.88 to 1.17)); when no operation was performed the mortality rate was higher in women, but not significantly so (OR 1.14 (0.91 to 1.42)).
Women with a ruptured AAA were less likely to be treated surgically than men, and their overall mortality rate was higher. Lower rates of surgery in women than in men may contribute to the higher mortality in women, but other explanations are possible.
对英格兰腹主动脉瘤(AAA)破裂入院治疗的女性和男性在治疗及预后方面的差异进行了研究。
分析了与死亡记录相关的医院事件统计中常规收集的英格兰AAA破裂急诊入院数据。计算了接受手术修复的患者百分比、30天病死率以及年龄调整后的比值比(OR),对女性和男性进行了比较。
共有2463名女性和7615名男性因AAA破裂的初步诊断入院(平均年龄分别为79.8岁和74.9岁);39.6%的女性和66.4%的男性接受了手术修复(OR 0.47(95%置信区间0.42至0.52))。总体而言,75.6%的女性和61.7%的男性在入院30天内死亡(OR 1.36(1.22至1.52))。接受手术的女性和男性死亡率相似(OR 1.01(0.88至1.17));未进行手术时,女性死亡率较高,但差异不显著(OR 1.14(0.91至1.42))。
AAA破裂的女性接受手术治疗的可能性低于男性,且其总体死亡率更高。女性手术率低于男性可能是导致女性死亡率较高的原因,但也可能有其他解释。