TMD Clinic, Department of Maxillofacial Surgery, University of Padova, Italy.
Int J Oral Maxillofac Surg. 2012 Apr;41(4):506-13. doi: 10.1016/j.ijom.2011.11.007. Epub 2011 Dec 16.
The aim of the study was to compare the effectiveness of five weekly two-needle arthrocentesis plus hyaluronic injections vs. the same protocol performed with a single-needle technique in patients with inflammatory-degenerative disorders of the temporomandibular joint (TMJ). 80 patients with TMJ osteoarthritis were randomly assigned to the two-needle or single-needle protocol and followed up for 6 months after treatment. Several outcome parameters, such as maximum pain at rest and maximum pain on chewing, subjective chewing efficiency, limitation in jaw function, jaw range of motion in mm, were recorded at baseline and multiple follow up assessments. Both treatment groups recorded significant improvement with respect to baseline levels in almost all outcome variables. The rate of improvement was not significantly different between the treatment protocols in any of the outcome variables (p-values between 0.143 and 0.970). No between-group differences emerged for the perceived subjective efficacy (p=0.321) and the treatment tolerability (p=0.783). The present investigation did not support the existence of significant differences in the treatment effectiveness for inflammatory-degenerative TMJ disorders of a cycle of five weekly injections of arthrocentesis plus hyaluronic acid injections performed according to the classical two-needle or the single-needle technique.
本研究旨在比较每周两次两针关节内穿刺加透明质酸注射与单次一针技术在治疗颞下颌关节（TMJ）炎性退行性疾病患者中的疗效。80 例 TMJ 骨关节炎患者随机分为两针或单针方案，治疗后随访 6 个月。在基线和多次随访评估时记录了几个结局参数，如静息时最大疼痛和咀嚼时最大疼痛、主观咀嚼效率、下颌功能受限、颌运动幅度（mm）。两组患者在几乎所有结局变量方面均较基线水平有显著改善。在任何结局变量中，两种治疗方案的改善率均无显著差异（p 值介于 0.143 和 0.970 之间）。在主观疗效感知（p=0.321）和治疗耐受性（p=0.783）方面，两组间也未出现差异。本研究结果不支持每周五次注射关节内穿刺加透明质酸注射的治疗效果存在显著差异，这些注射是根据经典的两针或单针技术进行的。
