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通过检测中性粒细胞和外周血淋巴细胞中的酸性磷酸酶水平对过敏性和非过敏性皮炎进行鉴别诊断

[Differential diagnosis of allergic and non-allergic dermatitis by measuring the levels of acid phosphatase in neutrophils and peripheral blood lymphocytes].

作者信息

Kieć-Swierczyńska M, Prazanowski M, Skulimowska H

机构信息

Instytutu Medycyny Pracy im. prof. dr med. Jerzego Nofera w Lodzi.

出版信息

Przegl Dermatol. 1990 Mar-Apr;77(2):102-6.

PMID:2217834
Abstract

Using the cytoenzymatic method acid phosphatase was determined in peripheral blood neutrophils and lymphocytes in 25 patients with allergic eczema, 31 patients with eczema due to irritants and 18 clinically healthy subjects. In patients with allergic eczema the percent of neutrophils and lymphocytes containing acid phosphatase was decreased and the activity of this enzyme in neutrophils was reduced. In patients with non allergic eczema these values were normal. The method of determination of acid phosphate in neutrophils and lymphocytes is regarded as useful for the differentiation between both types of eczema.

摘要

采用细胞酶法对25例过敏性湿疹患者、31例刺激性湿疹患者和18名临床健康受试者的外周血中性粒细胞和淋巴细胞中的酸性磷酸酶进行了测定。在过敏性湿疹患者中,含酸性磷酸酶的中性粒细胞和淋巴细胞百分比降低,该酶在中性粒细胞中的活性降低。在非过敏性湿疹患者中,这些值是正常的。中性粒细胞和淋巴细胞中酸性磷酸酶的测定方法被认为有助于区分这两种类型的湿疹。

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