[Acetylation phenotype as a risk factor of diabetic neuropathy].

Acetylation phenotype was determined in 184 diabetics: 102 patients with Type I (insulin-dependent) and 82 patients with Type II (non-insulin-dependent) diabetes mellitus, who underwent complex investigations to assess the development of sensorimotor and autonomic neuropathy. The control group consisted of 121 healthy subjects of the same age distribution. The results obtained imply that the slow acetylation phenotype may be considered as a significant risk factor of diabetic neuropathy.