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关于贝壳杉烷和诺卡烷二萜及其药理学研究的综述。

A review on cassane and norcassane diterpenes and their pharmacological studies.

机构信息

Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Chattar Manzil Palace, Lucknow, India.

出版信息

Fitoterapia. 2012 Mar;83(2):272-80. doi: 10.1016/j.fitote.2011.12.007. Epub 2011 Dec 9.

Abstract

The natural Cassane and norcassane diterpenes are biosynthetic rearrangement products of Pimarane precursor in the biosynthetic pathway of diterpenes. Their distribution is highly restricted to various genera of Fabaceae family (especially to Caesalpinia genus). A comprehensive account of the structural diversity (322 structures, 114 references) is given in this review along with biological activities of cassane and norcassane diterpenes up to September 2011.

摘要

天然贝壳杉烷和去甲贝壳杉烷二萜是二萜生物合成途径中松烷前体的生物合成重排产物。它们的分布高度局限于豆科植物(特别是云实属)的各个属。本文综述了截至 2011 年 9 月贝壳杉烷和去甲贝壳杉烷二萜的结构多样性(322 个结构,114 个参考文献)及其生物活性。

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