Riediger C, Nietlispach F, Rüter F, Fassl J
Departement für Anästhesie und Intensivmedizin, Universitätsspital Basel, Schweiz.
Anaesthesist. 2011 Dec;60(12):1095-108. doi: 10.1007/s00101-011-1972-2.
Surgical replacement of aortic valves is the gold standard for therapy of high grade aortic valve stenosis. However, the changes in demography confront the responsible medical discipline with an increasingly higher risk profile of patients which necessitates the development of new less invasive alternative forms of treatment for the surgical therapy of aortic valve stenosis. This developmental process has progressed from mini-thoracotomy to transcatheter aortic valve implantation (TAVI). The TAVI procedure is a new therapeutic option for treatment of patients with high grade aortic valve stenosis and high perioperative morbidity and mortality risks with conventional aortic valve replacement. Because TAVI can be carried out while the heart is still beating and without a sternotomy or heart-lung maschine, this procedure is particularly suitable for elderly multimorbid patients and/or patients with previous cardiac surgery. The initial results of large prospective multicenter studies underline the value of TAVI in the modern treatment of high risk patients with symptomatic aortic valve stenosis. In addition to an understanding of the surgical procedure, anesthetists must have precise knowledge of the perioperative anesthesia management and possible complications of the procedure.
主动脉瓣置换手术是重度主动脉瓣狭窄治疗的金标准。然而,人口结构的变化使相关医学学科面临的患者风险状况越来越高,这就需要开发新的、侵入性较小的替代治疗方式来治疗主动脉瓣狭窄。这一发展过程已从微创开胸手术发展到经导管主动脉瓣植入术(TAVI)。TAVI手术是治疗重度主动脉瓣狭窄且传统主动脉瓣置换术围手术期发病率和死亡率风险高的患者的一种新的治疗选择。由于TAVI可以在心脏仍在跳动时进行,无需开胸或使用心肺机,因此该手术特别适合老年多病患者和/或曾接受过心脏手术的患者。大型前瞻性多中心研究的初步结果强调了TAVI在现代治疗有症状的高危主动脉瓣狭窄患者中的价值。除了了解手术过程外,麻醉医生还必须对围手术期麻醉管理及该手术可能出现的并发症有精确的认识。