Wolfe F
University of Kansas School of Medicine, Wichita.
Rheum Dis Clin North Am. 1990 Aug;16(3):681-98.
There has been confusion surrounding regional medical conditions, primary psychological conditions, and fibromyalgia in practice and in the literature. Confusing terminology and inappropriate use of diagnostic criteria have contributed to this problem. Use of the 1990 ACR Criteria for the Classification of Fibromyalgia together with the symptom and physical examination definitions in that report should go far to correct these problems. Problems of selection and identification bias filter patients with the syndrome, and almost all reports concerning the disorder have been obtained from subspecialty clinics. Almost nothing is known about fibromyalgia in the community, and characteristics of patients noted in the clinic may be a primary function of these biases. In general, in the clinic, about 90% of patients are women of a mean age slightly less than 50 years. Onset is noted in childhood and in old age, but most commonly in middle life. Trauma, surgery, and infection have been noted in association with development of the syndrome in some reports. More than 10% of patients attending general medical clinics and 15-20% attending rheumatology clinics have the syndrome. Chronicity is the rule. Work disability occurs, but most patients seem to be able to work, although some have changed jobs to accomplish this. Psychologic abnormalities are noted in most, but not all, reports, but may reflect selection bias and could be absent in the community.
在临床实践和文献中,对于区域性医学病症、原发性心理病症以及纤维肌痛一直存在混淆。令人困惑的术语和诊断标准的不当使用导致了这一问题。采用1990年美国风湿病学会(ACR)纤维肌痛分类标准以及该报告中的症状和体格检查定义,将在很大程度上纠正这些问题。选择和识别偏差问题筛选出了患有该综合征的患者,几乎所有关于该病症的报告均来自专科诊所。对于社区中的纤维肌痛几乎一无所知,诊所中所记录的患者特征可能主要是这些偏差所致。一般而言,在诊所中,约90%的患者为女性,平均年龄略低于50岁。发病可见于儿童期和老年期,但最常见于中年。在一些报告中,创伤、手术和感染与该综合征的发生有关。在普通内科诊所就诊的患者中,超过10%患有该综合征,在风湿病诊所就诊的患者中,15% - 20%患有该综合征。慢性病是常见情况。工作能力丧失时有发生,但大多数患者似乎仍能工作,尽管有些患者为此更换了工作。在大多数但并非所有报告中都提到了心理异常情况,但这可能反映了选择偏差,在社区中可能并不存在。