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[颊咽癌的一期及修复性经上颌骨颊咽切除术]

[Primary and recovery transmaxillar buccopharyngectomy in buccopharyngeal cancers].

作者信息

Junien-Lavillauroy C, Barthez M, Bolla M, Roux O, Mouret P

机构信息

Chirurgie Cervico-Faciale des pays francophones, Nantes.

出版信息

Rev Laryngol Otol Rhinol (Bord). 1990;111(2):115-9.

PMID:2218113
Abstract

From january 1976 to december 1986, 78 patients were treated surgically for squamous cell carcinoma of the lateral buccopharyngeal junction without chemotherapy at first. 36 patients were treated by primary surgery with post-operative radiotherapy and 31 patients were treated by recovery surgery. Post-operative course was uncomplicated in 41% of cases (39% in primary surgery, 43% in recovery surgery); in 14% of cases serious local complications were observed (11% in primary surgery, 17% in recovery surgery). Carcinological failures appeared in 46% of cases in primary surgery and in 70% of cases in recovery surgery. Three years and five years actuarial survival rate were 45% and 39% respectively in recovery surgery. Prognostic factors are studied: resection quality, histological metastasis in lymph nodes. The authors emphasize on the best control of the big tumors in primary surgery and on the best results with small ulcerated infiltrant carcinoma.

摘要

1976年1月至1986年12月,78例外侧颊咽交界处鳞状细胞癌患者首先未接受化疗而接受了手术治疗。36例患者接受了一期手术加术后放疗,31例患者接受了挽救性手术。41%的病例术后病程无并发症(一期手术为39%,挽救性手术为43%);14%的病例观察到严重的局部并发症(一期手术为11%,挽救性手术为17%)。一期手术46%的病例和挽救性手术70%的病例出现肿瘤学失败。挽救性手术的三年和五年精算生存率分别为45%和39%。对预后因素进行了研究:切除质量、淋巴结组织学转移。作者强调一期手术中对大肿瘤的最佳控制以及小溃疡浸润性癌的最佳治疗效果。

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