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[放射外科联合治疗外侧颊咽交界区肿瘤的不同方式]

[Different modalities of the radiosurgical combination in the treatment of tumors of lateral buccopharyngeal junction].

作者信息

Lefebvre J L, Vankemmel B, Coche-Dequeant B, Castelain B, Buisset E, Adenis L

出版信息

Ann Otolaryngol Chir Cervicofac. 1987;104(1):15-20.

PMID:3566046
Abstract

Results are presented of combined transmaxillary buccopharyngectomy-radiotherapy treatment of 290 tumors of lateral buccopharyngeal junction. Post-therapeutic course was uncomplicated but 8 postoperative deaths are reported. Secondary extension of tumor was noted in 109 patients and another cancer in 64. Actuarial survival at 3 years was 54%, at 5 years 39% and at 10 years 17%. Lingual and muscle extensions were the most difficult to control and first intention excision is therefore performed when bone invasion has occurred. In contrast, total dose radiotherapy should probably precede surgery for forms with lingual and/or muscle extension.

摘要

本文呈现了对290例颊咽外侧交界肿瘤行上颌骨联合颊咽切除术-放射治疗的结果。治疗后过程无并发症,但报告有8例术后死亡。109例患者出现肿瘤继发扩展,64例出现另一种癌症。3年精算生存率为54%,5年为39%,10年为17%。舌部和肌肉扩展最难控制,因此当发生骨侵犯时应进行一期切除。相比之下,对于有舌部和/或肌肉扩展的病例,手术前可能应先进行全剂量放疗。

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