Meunier F
Service de Médecine Interne, Institut Jules Bordet, Université Libre de Bruxelles, Belgique.
Rev Med Brux. 1990 Sep;11(7):278-82.
Invasive fungal infections are major problems in immunocompromised patients and optimal therapeutical modalities are still far from optimal. Recently, progresses of antifungal therapy have been achieved with the development of new antifungal agents. In particular, fluconazole seems very promising due to the availability of oral and intravenous formulations. Tolerance and compliance of patients are excellent and side effects as well as interaction with other drugs are less commonly observed than with other antifungal agents available so far. The major indications of fluconazole are candidiasis and cryptococcosis.
侵袭性真菌感染是免疫功能低下患者面临的主要问题，而最佳治疗方式仍远非理想状态。近年来，随着新型抗真菌药物的研发，抗真菌治疗取得了进展。特别是氟康唑，由于有口服和静脉注射剂型，似乎非常有前景。患者的耐受性和依从性良好，与其他现有抗真菌药物相比，副作用以及与其他药物的相互作用较少见。氟康唑的主要适应证为念珠菌病和隐球菌病。
