Research on Research Group, Department of Surgery, Duke University Medical Center, DUMC 3094, Durham, NC 27710, USA.
Obes Surg. 2012 Feb;22(2):220-9. doi: 10.1007/s11695-011-0575-y.
Gallstone formation is common in obese patients, particularly during rapid weight loss. Whether a concomitant cholecystectomy should be performed during laparoscopic gastric bypass surgery is still contentious. We aimed to analyze trends in concomitant cholecystectomy and laparoscopic gastric bypass surgery (2001-2008), to identify factors associated with concomitant cholecystectomy, and to compare short-term outcomes after laparoscopic gastric bypass with and without concomitant cholecystectomy.
We used data from adults undergoing laparoscopic gastric bypass for obesity from the Nationwide Inpatient Sample. The Cochran-Armitage trend test was used to assess changes over time. Unadjusted and risk-adjusted generalized linear models were performed to assess predictors of concomitant cholecystectomy and to assess postoperative short-term outcomes.
A total of 70,287 patients were included: mean age was 43.1 years and 81.6% were female. Concomitant cholecystectomy was performed in 6,402 (9.1%) patients. The proportion of patients undergoing concomitant cholecystectomy decreased significantly from 26.3% in 2001 to 3.7% in 2008 (p for trend < 0.001). Patients who underwent concomitant cholecystectomy had higher rates of mortality (unadjusted odds ratios [OR], 2.16; p = 0.012), overall postoperative complications (risk-adjusted OR, 1.59; p = 0.001), and reinterventions (risk-adjusted OR, 3.83; p < 0.001), less frequent routine discharge (risk-adjusted OR, 0.70; p = 0.05), and longer adjusted hospital stay (median difference, 0.4 days; p < 0.001).
Concomitant cholecystectomy and laparoscopic gastric bypass surgery have decreased significantly over the last decade. Given the higher rates of postoperative complications, reinterventions, mortality, as well as longer hospital stay, concomitant cholecystectomy should only be considered in patients with symptomatic gallbladder disease.
胆结石的形成在肥胖患者中很常见,尤其是在体重快速下降期间。在腹腔镜胃旁路手术中是否同时进行胆囊切除术仍存在争议。我们旨在分析腹腔镜胃旁路手术中同时进行胆囊切除术的趋势(2001-2008 年),确定与同时进行胆囊切除术相关的因素,并比较同时进行和不进行胆囊切除术的腹腔镜胃旁路手术后的短期结果。
我们使用来自全国住院患者样本的成年人接受腹腔镜胃旁路手术治疗肥胖的数据。采用 Cochran-Armitage 趋势检验来评估随时间的变化。进行未调整和风险调整的广义线性模型,以评估同时进行胆囊切除术的预测因素,并评估术后短期结果。
共纳入 70287 例患者:平均年龄为 43.1 岁,81.6%为女性。在 6402 例(9.1%)患者中进行了同时胆囊切除术。同时进行胆囊切除术的患者比例从 2001 年的 26.3%显著下降到 2008 年的 3.7%(趋势检验 p<0.001)。同时进行胆囊切除术的患者死亡率(未调整比值比 [OR],2.16;p=0.012)、总体术后并发症(风险调整 OR,1.59;p=0.001)和再次干预(风险调整 OR,3.83;p<0.001)的发生率更高,常规出院的频率较低(风险调整 OR,0.70;p=0.05),调整后的住院时间更长(中位数差异,0.4 天;p<0.001)。
在过去十年中,同时进行胆囊切除术和腹腔镜胃旁路手术的比例显著下降。鉴于术后并发症、再次干预、死亡率以及住院时间更长的发生率更高,只有在有症状的胆囊疾病患者中才应考虑同时进行胆囊切除术。