Department of Surgery, Oregon Health and Science University, Portland, Oregon.
Department of Surgery, University of California, San Francisco, California.
Surg Obes Relat Dis. 2019 Jun;15(6):864-870. doi: 10.1016/j.soard.2019.03.004. Epub 2019 Mar 20.
Gallstone disease occurs more commonly in the obese population and is often diagnosed during the preoperative evaluation for bariatric surgery.
This study analyzed outcomes of laparoscopic gastric bypass (LGB) and laparoscopic sleeve gastrectomy (SG), with and without cholecystectomy (LC), using data from the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program.
Patients reported to Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program participating centers in the United States and Canada in 2015.
All cases of LGB and SG, with and without LC, were analyzed. A 1:1 propensity-matched cohort was created for both SG and LGB, with and without concomitant LC. Multivariate logistic regression stratified by procedure was used to identify predictors of major complications after SG and LGB, using concomitant LC as a predictor. We also constructed a model for surgical site infections (SSIs) for SG group.
Of 98,292 sleeve operations, 2046 (2%) had concomitant LC. Of 44,427 bypass operations, 1426 (3%) had concomitant LC. For the sleeve group, concomitant LC increased operative time by an average of 27 minutes but did not affect length of stay, mortality, or major complications. Concomitant LC was associated with increased SSI (1% versus .4%) and need for reoperation (1.6% versus .7%) in univariate models. After adjusting for other predictors, concomitant LC was associated with increased risk for SSI (odds ratio 2.5, confidence interval 1.0-5.9, P = .04). For the bypass group, concomitant LC increased operative time by an average of 28 minutes to the operation, and postoperative length of stay averaged ∼5 hours longer (2.4 versus 2.2 d, P = .03). Thirty-day complications were similar between the groups. On multivariate analysis, concomitant LC was not a significant risk factor for major complications. Only operative time was an independent factor for major complications.
Concomitant LC with laparoscopic sleeve gastrectomy or gastric bypass did not affect mortality or risk of major complication. For sleeve patients, concomitant LC was associated with a .6% increased risk (.4% to 1.0%) of SSI. Concomitant LC with laparoscopic sleeve gastrectomy or gastric bypass is safe when indicated for gallstone disease.
胆石病在肥胖人群中更为常见,并且常在减重手术的术前评估中被诊断。
本研究使用美国和加拿大代谢和减重手术认证和质量改进计划的数据,分析腹腔镜胃旁路术(LGB)和腹腔镜袖状胃切除术(SG),以及伴或不伴胆囊切除术(LC)的结果。
2015 年,在美国和加拿大的代谢和减重手术认证和质量改进计划参与中心报告的所有 LGB 和 SG 病例,以及伴或不伴 LC。
分析所有 LGB 和 SG 伴或不伴 LC 的病例。对 SG 和 LGB 伴或不伴 LC 分别创建了 1:1 的倾向匹配队列。采用多变量逻辑回归,根据手术分层,以 LC 为预测因子,确定 SG 和 LGB 术后主要并发症的预测因素。我们还为 SG 组构建了手术部位感染(SSI)模型。
在 98292 例袖套手术中,有 2046 例(2%)伴 LC;在 44427 例旁路手术中,有 1426 例(3%)伴 LC。对于袖套组,LC 平均增加手术时间 27 分钟,但不影响住院时间、死亡率或主要并发症。在单变量模型中,LC 与 SSI(1%比 0.4%)和需要再次手术(1.6%比 0.7%)增加有关。在调整其他预测因素后,LC 与 SSI 风险增加相关(比值比 2.5,95%置信区间 1.0-5.9,P =.04)。对于旁路组,LC 平均增加手术时间 28 分钟,术后住院时间平均延长约 5 小时(2.4 比 2.2 天,P =.03)。两组 30 天并发症相似。多变量分析显示,LC 不是主要并发症的显著危险因素。只有手术时间是主要并发症的独立因素。
腹腔镜袖套胃切除术或胃旁路术伴 LC 并不影响死亡率或主要并发症的风险。对于袖套组患者,LC 与 SSI 风险增加 0.6%(0.4%至 1.0%)相关。当存在胆囊结石时,腹腔镜袖套胃切除术或胃旁路术伴 LC 是安全的。