Halicioglu Oya, Sutcuoglu Sumer, Koc Feyza, Ozturk Can, Albudak Esin, Colak Ayfer, Sahin Ebru, Asik Akman Sezin
Department of Pediatrics, The Ministry of Health Tepecik Teaching and Research Hospital, Izmir, Turkey.
J Matern Fetal Neonatal Med. 2012 Sep;25(9):1618-21. doi: 10.3109/14767058.2011.648244. Epub 2012 Feb 1.
To investigate the frequencies of vitamin B12 and folate deficiencies in pregnant women in low socioeconomic group, the relation between the animal-source foods consumption and maternal vitamin B12-folate statuses, and their impacts on anthropometric measurements of the infants.
A total of 208 pregnant women in the last trimester were included in the study. A questionnaire about socio-demographic status, consumption of meat, egg, milk-dairy products, multivitamin supplementation was used. Vitamin B(12) and folate concentrations were studied by chemiluminescence method. The babies of Vitamin B(12) deficient mothers were evaluated after birth.
The rate of vitamin B(12) deficiency was 47.6% and folate deficiency was 17.3% of pregnant women. Animal food consumption was inadequate about half of pregnant women and vitamin B(12) levels in these women were significantly low. There were no statistically significant relationships between the birth weight, birth length and head circumference measurements, and maternal vitamin B(12) and folate concentrations.
The rate of vitamin B12 deficiency in pregnant women in low socioeconomic population is high. Although there were no significant effects of the vitamin B12 and folate deficiencies on birth size, additional studies are required to elucidate the subsequent effects.
调查社会经济地位较低群体中孕妇维生素B12和叶酸缺乏的发生率、动物源性食物摄入量与孕妇维生素B12 - 叶酸状态之间的关系，以及它们对婴儿人体测量指标的影响。
本研究纳入了208名孕晚期孕妇。使用了一份关于社会人口学状况、肉类、蛋类、奶类 - 奶制品摄入量及复合维生素补充情况的问卷。采用化学发光法研究维生素B12和叶酸浓度。对维生素B12缺乏母亲所生的婴儿在出生后进行评估。
孕妇中维生素B12缺乏率为47.6%，叶酸缺乏率为17.3%。约一半孕妇的动物性食物摄入量不足，这些孕妇的维生素B12水平显著偏低。出生体重、出生身长和头围测量值与孕妇维生素B12和叶酸浓度之间无统计学显著关系。
社会经济地位较低人群中孕妇的维生素B12缺乏率较高。尽管维生素B12和叶酸缺乏对出生大小无显著影响，但仍需要进一步研究以阐明其后续影响。
