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病例报告631:多腺体自身免疫(施密特)综合征中的新骨疏松症(干骺端骨质减少)

Case report 631: Neo-osseous porosis (metaphyseal osteopenia) in polyglandular autoimmune (Schmidt) syndrome.

作者信息

Vela B S, Dorin R I, Hartshorne M F

机构信息

Department of Medicine, Albuquerque Veterans Administration Medical Center, NM 87108.

出版信息

Skeletal Radiol. 1990;19(6):468-71. doi: 10.1007/BF00241809.

DOI:10.1007/BF00241809
PMID:2218600
Abstract

In summary, a case is reported of a patient with the radiographic findings of diffuse, symmetrical metaphyseal osteopenia of long bones. A constellation termed neo-osseous porosis, associated with polyendocrine failure (Schmidt syndrome) involving the thyroid gland, adrenal glands, and gonads has been described in this case. Neo-osseous porosis has been observed previously in idiopathic juvenile osteoporosis. This case represents the first instance in which this distinctive radiographic picture has been observed in the setting of specific (multiple) endocrine dysfunction disorders.

摘要

总之,本文报告了一例患者,其长骨的X线表现为弥漫性、对称性干骺端骨质减少。该病例中描述了一种称为新骨疏松症的症候群,它与涉及甲状腺、肾上腺和性腺的多内分泌腺功能减退(施密特综合征)相关。新骨疏松症先前已在特发性青少年骨质疏松症中观察到。该病例是首次在特定(多种)内分泌功能障碍性疾病背景下观察到这种独特的X线表现。

相似文献

1
Case report 631: Neo-osseous porosis (metaphyseal osteopenia) in polyglandular autoimmune (Schmidt) syndrome.病例报告631:多腺体自身免疫(施密特)综合征中的新骨疏松症(干骺端骨质减少)
Skeletal Radiol. 1990;19(6):468-71. doi: 10.1007/BF00241809.
2
[Autoimmune polyglandular syndrome. Clinical experience in 21 cases].[自身免疫性多腺体综合征。21例临床经验]
Rev Med Chil. 1990 Jun;118(6):635-42.
3
Polyglandular autoimmune syndromes.多腺体自身免疫综合征
Am J Med Sci. 1985 Aug;290(2):77-88. doi: 10.1097/00000441-198508000-00007.
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Development of type II autoimmune polyglandular syndrome in a patient with idiopathic thrombocytopenic purpura.
Isr J Med Sci. 1988 Jan;24(1):57-8.
5
Autoimmune polyglandular syndromes.自身免疫性多内分泌腺综合征
Pediatr Ann. 1980 Apr;9(4):154-62.
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Pure red cell hypoplasia associated with polyglandular autoimmune syndrome type I.
Isr J Med Sci. 1989 Mar;25(3):138-41.
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[Polyglandular autoimmune failure].[多腺体自身免疫性衰竭]
Harefuah. 1988 May 15;114(10):481-3.
8
[Type II autoimmune polyglandular syndrome associated with empty sella turcica].
An Med Interna. 1989 Feb;6(2):89-91.
9
Endocrine-skin interactions. Cutaneous manifestations of adrenal disease, pheochromocytomas, carcinoid syndrome, sex hormone excess and deficiency, polyglandular autoimmune syndromes, multiple endocrine neoplasia syndromes, and other miscellaneous disorders.内分泌与皮肤的相互作用。肾上腺疾病、嗜铬细胞瘤、类癌综合征、性激素过多与不足、多腺体自身免疫综合征、多发性内分泌肿瘤综合征及其他杂症的皮肤表现。
J Am Acad Dermatol. 1988 Jul;19(1 Pt 1):1-20.
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本文引用的文献

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Differential effects of endocrine dysfunction on the axial and the appendicular skeleton.内分泌功能障碍对中轴骨骼和附属骨骼的不同影响。
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Effects of glucocorticoids on fetal rat bone collagen synthesis in vitro.糖皮质激素对体外培养的胎鼠骨胶原合成的影响。
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