Feingold K R, Elias P M
Dermatology Service, Veterans Administration Medical Center, San Francisco, CA 94121.
J Am Acad Dermatol. 1988 Jul;19(1 Pt 1):1-20.
Endocrinologic disorders occasionally manifest themselves by their associated and/or induced cutaneous abnormalities. In some instances, the initial and most prominent complaints of the patient are related to alterations in the skin, and therefore the dermatologist will at times be the first physician consulted. In this review we describe the cutaneous lesions that occur in patients with Cushing's syndrome, adrenal insufficiency, pheochromocytomas, carcinoid syndrome, sex hormone excess or deficiency, polyglandular autoimmune syndromes, and multiple neoplasia syndromes. Additionally, we discuss the relationship of acanthosis nigricans and xanthomas to endocrinologic disorders and the skin lesions that occur in association with the spotty pigmentation, myxoma, endocrine overactivity syndrome, and the polyneuropathy, organomegaly, endocrinopathy, M protein, skin changes (POEMS) syndrome.
内分泌紊乱偶尔会通过其相关的和/或诱发的皮肤异常表现出来。在某些情况下，患者最初和最突出的主诉与皮肤改变有关，因此皮肤科医生有时会成为首位被咨询的医生。在本综述中，我们描述了库欣综合征、肾上腺功能不全、嗜铬细胞瘤、类癌综合征、性激素过多或缺乏、多腺体自身免疫综合征以及多发性肿瘤综合征患者出现的皮肤病变。此外，我们还讨论了黑棘皮病和黄瘤与内分泌紊乱的关系，以及与斑点状色素沉着、黏液瘤、内分泌功能亢进综合征和多神经病、器官肿大、内分泌病、M蛋白、皮肤改变（POEMS）综合征相关的皮肤病变。
