Hunt S J, Johnson P C, Coons S W, Pittman H W
Division of Neuropathology, St. Joseph's Hospital and Medical Center, Phoenix, Arizona.
Surg Neurol. 1990 Nov;34(5):336-42. doi: 10.1016/0090-3019(90)90011-d.
Two neonates with intracranial teratomas presented with cranial enlargements a few weeks after birth. Both cases underwent surgery: one died intraoperatively; the other is the longest known survivor, alive 7 years and 9 months after subtotal excision of a mature teratoma of the left sylvian fissure. Previous operations have been relatively few and nearly all have been unsuccessful. Size and favorable location may be the most important prognostic features regardless of the histologic classification as mature or immature. One of our cases demonstrates that even subtotal excision of a mature teratoma can result in long-term survival.
两名患有颅内畸胎瘤的新生儿在出生后几周出现头颅增大。两例均接受了手术:一例术中死亡;另一例是已知存活时间最长的幸存者,在左侧外侧裂成熟畸胎瘤次全切除术后存活了7年9个月。以往的手术相对较少,且几乎都未成功。无论组织学分类为成熟型还是未成熟型,肿瘤大小和有利的位置可能是最重要的预后特征。我们的一个病例表明,即使是成熟畸胎瘤的次全切除也可导致长期存活。