Robles Fradejas M, Gonzalo García I, De Las Casas Quispe A C, Martin García A, García Higuera M I, Rodriguez Minguélez M, Martínez-Guisasola J
a Prenatal Diagnosis Unit, Department of Obstetrics and Gynecology.
b Department of Anatomic Pathology , and.
J Matern Fetal Neonatal Med. 2017 May;30(10):1139-1146. doi: 10.1080/14767058.2016.1205029. Epub 2016 Jul 11.
To describe a case diagnosed with intracranial teratoma in week 32 of gestation, as well as review of the literature in order to discern the appropriate treatment method and general prognosis of this anomaly.
A literature search was performed on the prenatal diagnosis of congenital intracranial teratomas in MEDLINE, EMBASE, Cochrane library data bases. Evaluated in this review are parameters such as time of prenatal diagnosis, associated pathology, size of tumors, method of terminating pregnancy, perinatal outcome and histological study of the tumor.
A total of 49 cases were found, of which 12 were finished gestation, 28 cesarean section was performed and only nine had vaginal delivery. All died in the neonatal period except in three cases with intrauterine death after diagnosis.
As the incidence of intracranial immature teratomas is very low and the prognosis is poor, their prenatal diagnosis and obstetric management present a great challenge for the planning of a follow-up and treatment of the disease in accordance with the preferences of the parents.
描述一例在妊娠32周时被诊断为颅内畸胎瘤的病例,并回顾相关文献,以明确该异常情况的合适治疗方法及总体预后。
在MEDLINE、EMBASE、Cochrane图书馆数据库中对先天性颅内畸胎瘤的产前诊断进行文献检索。本综述评估的参数包括产前诊断时间、相关病理、肿瘤大小、终止妊娠方法、围产期结局及肿瘤的组织学研究。
共找到49例病例,其中12例足月分娩,28例行剖宫产,仅9例经阴道分娩。除3例诊断后宫内死亡外,所有病例均在新生儿期死亡。
由于颅内未成熟畸胎瘤的发病率极低且预后不良,其产前诊断及产科管理对于根据父母意愿规划疾病的随访和治疗构成了巨大挑战。