Busch M, Dühmke E
Abteilung Strahlentherapie, Zentrum Radiologie, Georg-August-Universität Göttingen.
Strahlenther Onkol. 1990 Sep;166(9):591-4.
Optimization of brachytherapy means first of all a physical adaptation of isodoses to shape and tolerances of radiosensitive tissues surrounding the target volume, and also to shape and dosage requirements of the tumor to be treated. Dose computation algorithms for optimizing afterloading therapy postulate the discontinuous movement of the iridium source. A new method for the application of the discontinuous movement to our afterloading equipment was worked out. It combines the abilities of the source movements and the demands of the clinical optimization of the isodoses used for the brachytherapy of cervix carcinoma.
近距离放射治疗的优化首先意味着等剂量线在物理上要适应靶区周围放射敏感组织的形状和耐受性,也要适应待治疗肿瘤的形状和剂量要求。用于优化后装治疗的剂量计算算法假定铱源的运动是不连续的。我们研发出一种将这种不连续运动应用于后装设备的新方法。它结合了源运动的能力以及宫颈癌近距离放射治疗中临床等剂量线优化的要求。