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维生素 D 缺乏:儿科矫形学视角。

Vitamin D deficiency: a paediatric orthopaedic perspective.

机构信息

University Hospital Southampton, NHS Foundation Trust Southampton University Hospitals, Southampton General Hospital, Southampton, Hampshire, UK.

出版信息

Curr Opin Pediatr. 2012 Feb;24(1):46-9. doi: 10.1097/MOP.0b013e32834ec8eb.

DOI:10.1097/MOP.0b013e32834ec8eb
PMID:22189396
Abstract

PURPOSE OF REVIEW

At the turn of the last century, rickets (vitamin D deficiency) was one of the most common musculoskeletal diseases of the paediatric population presenting to physicians. Today, the most common referral pathway for these patients ends in a paediatric orthopaedic outpatient clinic. Vitamin D deficiency is a clinical entity that can affect all children and should be looked for in all children with musculoskeletal symptoms.

RECENT FINDINGS

The child at risk of rickets is now white, breastfed, protected from the sun and obese. Vitamin D deficiency can present as atypical muscular pain, pathological fractures or slipped upper femoral epiphysis. Obesity is linked with lower vitamin D levels; however, in the paediatric population, this does not necessarily equal clinical disorder. Vitamin D supplements can be used to reduce the risk of pathological fractures in the cerebral palsy child. It should also form part of the differential diagnosis in the work-up of nonaccidental injuries. Children with a low vitamin D present with a higher incidence of fractures from normal activities. Vitamin D levels need to be assessed before any form of orthopaedic surgery, as it can affect growth, both in the diaphysis of the bone and in the growth plate.

SUMMARY

Vitamin D levels are a key element in the successful practice of paediatric orthopaedics. It is not just the possible cause of disorder presenting to the clinician but also extremely important in ensuring the successful postoperative recovery of the patient.

摘要

目的综述

在上个世纪之交,佝偻病(维生素 D 缺乏症)是儿科医生最常见的肌肉骨骼疾病之一。如今,这些患者最常见的转诊途径是进入儿科矫形门诊。维生素 D 缺乏是一种可以影响所有儿童的临床病症,应在所有出现肌肉骨骼症状的儿童中寻找。

最新发现

现在患有佝偻病的儿童是白人、母乳喂养、避免阳光照射和肥胖的儿童。维生素 D 缺乏症可表现为非典型肌肉疼痛、病理性骨折或股骨上端滑脱。肥胖与维生素 D 水平较低有关;然而,在儿科人群中,这并不一定等于临床疾病。维生素 D 补充剂可用于降低脑瘫儿童病理性骨折的风险。它还应作为非故意损伤检查中的鉴别诊断的一部分。维生素 D 水平低的儿童在正常活动中骨折的发生率更高。在进行任何形式的矫形手术之前,都需要评估维生素 D 水平,因为它会影响骨骼的骨干和生长板的生长。

总结

维生素 D 水平是儿科矫形成功实践的关键因素。它不仅是导致患者出现临床疾病的可能原因,而且对于确保患者术后成功康复也非常重要。

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