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急性结直肠癌梗阻的应急处理。

Emergency management of acute colonic cancer obstruction.

机构信息

Department of Digestive Surgery, CHU Dupuytren, 2, avenue Martin-Luther-King, 87042 Limoges cedex, France.

出版信息

J Visc Surg. 2012 Feb;149(1):e3-e10. doi: 10.1016/j.jviscsurg.2011.11.003. Epub 2011 Dec 19.

Abstract

Emergency management of obstructing colonic cancer depends on both tumor location and stage, general condition of the patient and surgeon's experience. Right sided or transverse colon obstructing cancers are usually treated by right hemicolectomy-extended if necessary to the transverse colon-with primary anastomosis. For left-sided obstructing cancer, in patients with low surgical risk, primary resection and anastomosis associated with on-table irrigation or manual decompression can be performed. It prevents the confection of a loop colostomy but presents the risk of anastomotic leakage. Subtotal or total colectomy allows the surgeon to encompass distended and fecal-loaded colon, and to perform one-stage resection and anastomosis. Its disadvantage is an increased daily frequency of stools. It must be performed only in cases of diastatic colon perforation or synchronous right colonic cancer. In patients with high surgical risk, Hartmann procedure must be preferred. It allows the treatment of both obstruction and cancer, and prevents anastomotic leakage but needs a second operation to reverse the colostomy. Colonic stenting is clinically successful in up to 90% in specialized groups. It is used as palliation in patients with disseminated disease or bridge to surgery in the others. If stent insertion is not possible, loop colostomy is still indicated in patients at high surgical risk.

摘要

结直肠梗阻的紧急处理取决于肿瘤的位置和分期、患者的一般情况以及外科医生的经验。右侧或横结肠梗阻性肿瘤通常通过右半结肠切除术(如有必要,可扩展至横结肠)进行治疗,并进行一期吻合。对于左侧梗阻性癌症,在手术风险较低的患者中,可以进行一期切除和吻合,同时进行术中灌洗或手动减压。这样可以避免造口,但存在吻合口漏的风险。次全结肠切除或全结肠切除可以使外科医生切除扩张和充满粪便的结肠,并进行一期切除和吻合。其缺点是每日排便次数增加。只有在结肠穿孔或同时存在右侧结肠癌的情况下才需要进行该手术。对于手术风险较高的患者,应首选 Hartmann 手术。该手术可以同时治疗梗阻和癌症,并预防吻合口漏,但需要再次手术来反转结肠造口。在专业团队中,经皮结肠支架置入术的临床成功率高达 90%。对于广泛转移疾病的患者,该手术可作为姑息治疗;对于其他患者,该手术可作为手术桥接。如果支架置入不可行,对于手术风险较高的患者,仍应进行肠造口术。

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