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胰岛素泵治疗在老年和年轻的1型糖尿病患者中同样有效且安全。

Insulin pump therapy is equally effective and safe in elderly and young type 1 diabetes patients.

作者信息

Matejko Bartlomiej, Cyganek Katarzyna, Katra Barbara, Galicka-Latala Danuta, Grzanka Malgorzata, Malecki Maciej T, Klupa Tomasz

机构信息

Department of Metabolic Diseases, Jagiellonian University, Medical College, 15 Kopernika Street, 31-501 Krakow, Poland.

出版信息

Rev Diabet Stud. 2011 Summer;8(2):254-8. doi: 10.1900/RDS.2011.8.254. Epub 2011 Aug 10.

Abstract

OBJECTIVES

It is generally accepted that in adult type 1 diabetes patients (T1D) continuous subcutaneous insulin infusion (CSII) via a personal pump is more effective than the multiple daily injections (MDI) model. However, it is not clear whether all age groups of adult T1D patients may equally benefit from CSII therapy. We aimed to compare the glycemic control and use of selected pump tools in T1D subjects using CSII over the age of 50 (50+ T1D) with patients younger than 50 years of age.

METHODS

The last available insulin pump/blood glucose meter downloads and last available HbA1c levels of 124 adult T1D subjects using CSII were reviewed. We divided our cohort into two subgroups: 50+ T1D patients (n = 13) and younger patients (n = 111).

RESULTS

There were no differences in glycemic control achieved with CSII treatment in 50+ T1D patients vs. younger subjects. HbA1c levels were 7.01 ± 0.67% and 7.34 ± 1.24% (p = 0.46), and the mean glycemia based on glucometer downloads was 141.8 ± 17.7 mg/dl and 150.8 ± 35.7 mg/dl (p = 0.69), respectively. Also, there were no differences with respect to the use of important personal pump options and tools.

CONCLUSION

In conclusion, insulin pump therapy appears to be effective and safe in T1D patients regardless of age.

摘要

目的

人们普遍认为,对于成年1型糖尿病患者(T1D),通过个人胰岛素泵进行持续皮下胰岛素输注(CSII)比多次皮下注射(MDI)模式更有效。然而,目前尚不清楚所有年龄组的成年T1D患者是否都能同样从CSII治疗中获益。我们旨在比较50岁及以上使用CSII的T1D患者(50 + T1D)与50岁以下患者的血糖控制情况以及所选胰岛素泵工具的使用情况。

方法

回顾了124名使用CSII的成年T1D患者的最后一次胰岛素泵/血糖仪下载数据以及最后一次可用的糖化血红蛋白(HbA1c)水平。我们将队列分为两个亚组:50 + T1D患者(n = 13)和较年轻患者(n = 111)。

结果

50 + T1D患者与较年轻患者在CSII治疗实现的血糖控制方面没有差异。HbA1c水平分别为7.01±0.67%和7.34±1.24%(p = 0.46),基于血糖仪下载数据的平均血糖分别为141.8±17.7mg/dl和150.8±35.7mg/dl(p = 0.69)。此外,在重要的个人胰岛素泵选项和工具的使用方面也没有差异。

结论

总之,胰岛素泵治疗对于T1D患者似乎无论年龄大小都是有效且安全的。

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