Faculdade de Medicina de Sobral, Universidade Federal do Ceará, Sobral, CE, Brazil.
Braz J Psychiatry. 2011 Dec;33(4):332-7. doi: 10.1590/s1516-44462011000400005.
To determine the correlation between depression and quality of life (QOL) of patients in hemodialysis (HD).
One hundred and sixty six patients over 18 years of age who had been in HD for at least three months and had no history of transplant. QOL was assessed using the SF-36. To categorize depression, a score > 10 was used on the 10-item version of the Center for Epidemiologic Studies Depression Scale (CES-D). Comparisons between depressed and nondepressed patients were performed using the chi-square test, Student's t-test, and Mann-Whitney test. Multiple regression was performed to assess the predictive variables of patients' QOL.
Symptoms of depression were found in 13 (7.8%) patients. The only variable that differed among depressed patients was QOL. Depressed patients presented lower scores in vitality (40.7 vs. 57.3; p = 0.010), role-emotional (25.6 vs. 62.5; p = 0.006), and mental health (50.1 vs. 65.4; p = 0.023). Regression analysis demonstrated that depression was a predictor of role-emotional (OR = 0.981, CI = 0.967-0.996; p = 0.010) and mental health (OR = 0.970, CI = 0.946-0.996; p = 0.022).
Depressed patients experience a poor QOL because, in addition to their chronically affected physical aspects, they also feel limited in the mental dimensions, which usually have the highest score among non-depressed HD patients.
探讨血液透析（HD）患者抑郁与生活质量（QOL）的相关性。
选择 166 例年龄＞18 岁、透析时间≥3 个月且未接受过移植的患者，采用 SF-36 量表评估 QOL，采用抑郁自评量表（CES-D）10 项版本对患者进行抑郁评估，得分＞10 分者诊断为抑郁。采用卡方检验、t 检验和 Mann-Whitney 检验比较抑郁组和非抑郁组患者的差异，采用多元逐步回归分析评估患者 QOL 的预测变量。
13 例（7.8%）患者存在抑郁症状。抑郁患者与非抑郁患者仅在 QOL 方面存在差异。与非抑郁患者相比，抑郁患者的活力评分（40.7 比 57.3；p = 0.010）、角色情感评分（25.6 比 62.5；p = 0.006）和心理健康评分（50.1 比 65.4；p = 0.023）较低。回归分析显示，抑郁是角色情感（OR = 0.981，95%CI：0.967-0.996；p = 0.010）和心理健康（OR = 0.970，95%CI：0.946-0.996；p = 0.022）的预测因素。
抑郁患者的 QOL 较差，除了身体状况长期受影响外，他们在心理方面也感到受限，而心理方面通常是非抑郁 HD 患者得分最高的方面。
