Department of Orthopedic Surgery, Nagasaki Medical Center, 2-1001-1 Kubara, Omura, 852-8562, Japan.
Int Orthop. 2012 Jun;36(6):1163-6. doi: 10.1007/s00264-011-1446-9. Epub 2011 Dec 22.
Heterotopic ossification (HO) after total hip arthroplasty (THA) is a frequent complication that compromises the success of this procedure; however, its precise pathogenesis is unknown. Patient-related risk factors have previously been investigated to predict patients likely to have HO. In this study, we compared bone mineral density (BMD) between patients with and without HO after THA.
We measured BMD of the lumbar spine, radius, and calcaneus using dual-energy X-ray absorptiometry in 98 females who were scheduled to undergo THA. Radiographs were graded for the presence of HO according to the criteria of Brooker at a minimum follow-up of two years following THA. BMD were compared between those with HO and those without.
In total, HO was observed in 20 of 98 hips. There were no significant differences in age, height, weight, body mass index, and pre-operative total hip score between the HO and non-HO groups. No significant difference was observed in BMD of the lumbar spine, distal radius, mid-radius, and calcaneus between the two groups.
Our findings suggest that generalized BMD is not related to the occurrence of HO after THA in women.
全髋关节置换术后(THA)异位骨化(HO)是一种常见的并发症,会影响该手术的成功率;然而,其确切的发病机制尚不清楚。先前已经研究了与患者相关的危险因素,以预测可能发生 HO 的患者。在这项研究中,我们比较了 THA 后有和没有 HO 的患者的骨密度(BMD)。
我们使用双能 X 线吸收仪测量了 98 名女性的腰椎、桡骨和跟骨的 BMD,这些女性计划接受 THA。在 THA 后至少两年的随访中,根据 Brooker 的标准对 X 线片进行 HO 存在的分级。比较 HO 组和非 HO 组之间的 BMD。
总共在 98 个髋关节中有 20 个观察到 HO。HO 组和非 HO 组在年龄、身高、体重、体重指数和术前全髋关节评分方面无显著差异。两组之间腰椎、远端桡骨、中段桡骨和跟骨的 BMD 无显著差异。
我们的研究结果表明,女性 THA 后全身 BMD 与 HO 的发生无关。