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Focus issue on male infertility.男性不育症专题
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The prevalence of midline prostatic cysts and the relationship between cyst size and semen parameters among infertile and fertile men.前列腺中线囊肿的患病率及囊肿大小与不孕和生育男性精液参数的关系。
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[Optimal evaluation of the infertile male. 2007 French urological association guidelines].[不育男性的最佳评估。2007年法国泌尿外科学会指南]
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Body mass index in relation to semen quality and reproductive hormones in New Zealand men: a cross-sectional study in fertility clinics.新西兰男性的体重指数与精液质量和生殖激素的关系:生育诊所的横断面研究。
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Causes of male infertility: a 9-year prospective monocentre study on 1737 patients with reduced total sperm counts.男性不育的原因:一项针对1737例精子总数减少患者的9年前瞻性单中心研究。
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Role of Imaging in the Evaluation of Male Infertility.影像学在男性不育评估中的作用。
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A method for utilizing automated machine learning for histopathological classification of testis based on Johnsen scores.基于约翰森评分的利用自动化机器学习进行睾丸组织病理学分类的方法。
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Semen parameters of non-infertile smoker and non-smoker men.非不育吸烟者与非吸烟者男性的精液参数。
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本文引用的文献

1
Fertility after cryptorchidism: epidemiology and other outcome studies.
Urology. 2005 Aug;66(2):427-31. doi: 10.1016/j.urology.2005.01.017.
2
Mumps orchitis and testicular atrophy; a factor in male sterility.流行性腮腺炎睾丸炎与睾丸萎缩;男性不育的一个因素。
Ann Intern Med. 1950 Jun;32(6):1075-86. doi: 10.7326/0003-4819-32-6-1075.
3
The spermatogenic potential of the undescended testis before and after treatment.
J Urol. 1960 May;83:697-705. doi: 10.1016/S0022-5347(17)65780-X.
4
A study of semen parameters with emphasis on sperm morphology in a fertile population: an attempt to develop clinical thresholds.一项针对可育人群精液参数的研究,重点关注精子形态:制定临床阈值的尝试。
Hum Reprod. 2001 Jan;16(1):110-114. doi: 10.1093/humrep/16.1.110.
5
Semen quality of workers occupationally exposed to hydrocarbons.
Fertil Steril. 2000 Feb;73(2):221-8. doi: 10.1016/s0015-0282(99)00515-4.
6
Factors associated with male infertility: a case-control study of 218 infertile and 240 fertile men.与男性不育相关的因素:一项针对218名不育男性和240名可育男性的病例对照研究。
BJOG. 2000 Jan;107(1):55-61. doi: 10.1111/j.1471-0528.2000.tb11579.x.
7
Semen quality and reproductive endocrine function in relation to biomarkers of lead, cadmium, zinc, and copper in men.男性精液质量和生殖内分泌功能与铅、镉、锌及铜生物标志物的关系
Environ Health Perspect. 2000 Jan;108(1):45-53. doi: 10.1289/ehp.0010845.
8
Relevance of male accessory gland infection for subsequent fertility with special focus on prostatitis.男性附属腺感染对后续生育能力的相关性,特别关注前列腺炎。
Hum Reprod Update. 1999 Sep-Oct;5(5):421-32. doi: 10.1093/humupd/5.5.421.
9
Hematopoietic and reproductive toxicity of 2-bromopropane, a recently introduced substitute for chlorofluorocarbons.
Toxicol Lett. 1999 Sep 5;108(2-3):309-13. doi: 10.1016/s0378-4274(99)00103-4.
10
Endocrine evaluation of infertile men.不育男性的内分泌评估。
Urology. 1997 Nov;50(5):659-64. doi: 10.1016/S0090-4295(97)00340-3.

男性不育症专题

Focus issue on male infertility.

作者信息

Kobayashi Hideyuki, Nagao Koichi, Nakajima Koichi

机构信息

Department of Urology, Toho University School of Medicine, Tokyo 143-8541, Japan.

出版信息

Adv Urol. 2012;2012:823582. doi: 10.1155/2012/823582. Epub 2011 Dec 1.

DOI:10.1155/2012/823582
PMID:22190920
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3235492/
Abstract

Male infertility problems can occur when sperms are limited in number or function. In this paper, we describe the clinical evaluation of male infertility. A detailed history, physical examination, and basic semen analysis are required. In addition, ultrasound, karyotyping, and hormonal studies are needed to determine specific causes of infertility. In addition, the World Health Organization (WHO, 2009) has developed a manual to provide guidance in performing a comprehensive semen analysis. Among the possible reasons for male infertility, nonobstructive azoospermia is the least treatable, because few or no mature sperm may be produced. In many cases, men with nonobstructive azoospermia typically have small-volume testes and elevated FSH. Although treatment may not completely restore the quality of semen from men with subnormal fertility, in some cases a successful pregnancy can still be achieved through assisted reproductive technology.

摘要

当精子数量或功能受限的时候,男性不育问题就可能出现。在本文中,我们描述了男性不育的临床评估。需要详细的病史、体格检查和基本精液分析。此外,还需要超声、染色体核型分析和激素研究来确定不育的具体原因。此外,世界卫生组织(WHO,2009年)编写了一本手册,为进行全面精液分析提供指导。在男性不育的可能原因中,非梗阻性无精子症是最难治疗的,因为可能很少或根本没有产生成熟精子。在许多情况下,患有非梗阻性无精子症的男性通常睾丸体积小且促卵泡激素升高。尽管治疗可能无法完全恢复生育能力低下男性的精液质量,但在某些情况下,通过辅助生殖技术仍可成功受孕。