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对于 Legg-Calvé-Perthes 病行货架手术治疗后,有哪些证据支持预防骨关节炎和改善股骨覆盖?

What is the evidence supporting the prevention of osteoarthritis and improved femoral coverage after shelf procedure for Legg-Calvé-Perthes disease?

机构信息

Department of Orthopaedic Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

出版信息

Clin Orthop Relat Res. 2012 Sep;470(9):2421-30. doi: 10.1007/s11999-011-2220-4.

Abstract

BACKGROUND

The evidence supporting continued use of shelf acetabuloplasty in Legg-Calvé-Perthes disease (LCPD) is not well-defined, and there is controversy regarding the long-term benefits related to clinical and functional improvement.

QUESTIONS/PURPOSES: Our goals were to determine whether shelf arthroplasty for LCPD (1) prevents the onset of early osteoarthritis; (2) improves pain, ROM, activity, and functional outcomes; (3) maintains or improves femoral head containment, sphericity, and congruency; (4) changes the acetabular index; and (5) is associated with a low rate of complications.

METHODS

We performed a systematic review of the medical literature from 1966 to 2009 using the search terms Perthes, shelf procedure, and acetabuloplasty. We excluded reports using multiple/combined treatment methods and those not clearly stratifying outcomes. Thirteen studies met the criteria. There were no Level I studies, one Level II prognostic study, five Level III therapeutic studies, and seven Level IV studies. Mean followup ranged from 2.6 to 17.9 years.

RESULTS

Only one study reported progression to early osteoarthritis in one patient. We found no evidence for improvement in ROM and continued pain relief at long-term followup. Mean decrease in lateral subluxation ratio was 13% to 30%, demonstrating an improvement in femoral head containment. Mean acetabular cover percentage improved 16% to 38%, and mean acetabular and center-edge angles improved 4° to 14° and 8° to 33°, respectively. There were no reports of any major complications after the procedure.

CONCLUSIONS

While radiographic measurements indicate improved coverage of the femoral head after shelf acetabuloplasty for LCPD, available evidence does not document the procedure prevents early onset of osteoarthritis or improves long-term function.

摘要

背景

在 Legg-Calvé-Perthes 病(LCPD)中,继续使用髋臼成形术的证据并不明确,并且关于临床和功能改善的长期益处存在争议。

问题/目的:我们的目标是确定髋臼成形术治疗 LCPD 是否(1)预防早期骨关节炎的发生;(2)改善疼痛、ROM、活动和功能结果;(3)维持或改善股骨头包容、球形度和一致性;(4)改变髋臼指数;(5)与低并发症发生率相关。

方法

我们使用 Perthes、shelf procedure 和 acetabuloplasty 等搜索词对 1966 年至 2009 年的医学文献进行了系统回顾。我们排除了使用多种/联合治疗方法的报告和未明确分层结果的报告。符合标准的有 13 项研究。没有一级研究,一项二级预后研究,五项三级治疗研究和七项四级研究。平均随访时间从 2.6 到 17.9 年不等。

结果

只有一项研究报告了一例患者进展为早期骨关节炎。我们没有发现 ROM 改善和长期随访时持续缓解疼痛的证据。外侧半脱位比的平均下降率为 13%至 30%,表明股骨头包容得到改善。髋臼覆盖率的平均改善为 16%至 38%,髋臼和中心边缘角分别改善了 4°至 14°和 8°至 33°。没有报告该手术后有任何重大并发症。

结论

虽然放射影像学测量表明髋臼成形术治疗 LCPD 后股骨头覆盖得到改善,但现有证据并未证明该手术可预防早期骨关节炎或改善长期功能。

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