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重新审视宽街水泵：弗吉尼亚州福雷斯特的奶牛场与正在爆发的炎症性肠病。

The Broad Street pump revisited: dairy farms and an ongoing outbreak of inflammatory bowel disease in Forest, Virginia.

机构信息

Division of Pediatric Gastroenterology, Hepatology and Nutrition, University of Virginia Children's Hospital, Box 800386 HSC, Charlottesville, Virginia 22908 USA.

出版信息

Gut Pathog. 2011 Dec 23;3(1):20. doi: 10.1186/1757-4749-3-20.

DOI:10.1186/1757-4749-3-20
PMID:22196128
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3287103/
Abstract

We report an ongoing outbreak of ulcerative colitis and Crohn's disease in Forest, Virginia involving 15 unrelated children and teenagers who resided in close proximity to dairy farms. Some of our cases demonstrated serologic evidence of Mycobacterium avium subspecies paratuberculosis infection, suggesting its potential role as an etiologic agent.

摘要

我们报告了一起正在弗吉尼亚州福雷斯特进行的溃疡性结肠炎和克罗恩病爆发，涉及 15 名无关联的儿童和青少年，他们居住在奶牛场附近。我们的一些病例表现出分支杆菌副结核亚种血清学证据，表明其可能作为病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5c3/3287103/8b1861fd58c1/1757-4749-3-20-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5c3/3287103/29167fb08a51/1757-4749-3-20-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5c3/3287103/8b1861fd58c1/1757-4749-3-20-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5c3/3287103/29167fb08a51/1757-4749-3-20-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5c3/3287103/8b1861fd58c1/1757-4749-3-20-2.jpg

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Gut Pathog. 2010 Dec 17;2(1):21. doi: 10.1186/1757-4749-2-21.
2
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Appl Environ Microbiol. 2010 Nov;76(21):7367-70. doi: 10.1128/AEM.00730-10. Epub 2010 Sep 3.
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Virulence. 2012 Oct 1;3(6):546-50. doi: 10.4161/viru.22121.
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