小鼠中的尿路上皮移植
Urothelial grafts in mice.
作者信息
Jones C R, Bradley N J, Davies A J, Williams G B
机构信息
Institute of Cancer Research, London, United Kingdom.
出版信息
Urology. 1990 Oct;36(4):350-2. doi: 10.1016/0090-4295(90)80246-j.
PMID:2219618
Abstract
Mouse bladder epithelium has been successfully transplanted to the bladders of syngeneic mice and has survived for at least twenty weeks. The fate of the transplanted tissue was followed using a fluorescein label. The recipient bladders were prepared by stripping the urothelium either by a surgical or a chemical method. The possibility of adopting a comparable technique for the treatment of early bladder cancer in man is discussed.
摘要
小鼠膀胱上皮已成功移植到同基因小鼠的膀胱中，并存活了至少二十周。使用荧光素标记追踪移植组织的命运。通过手术或化学方法剥脱尿路上皮来制备受体膀胱。文中讨论了采用类似技术治疗人类早期膀胱癌的可能性。
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