双相障碍中的从头 CNV：反复出现的主题还是新方向？
De novo CNVs in bipolar disorder: recurrent themes or new directions?
机构信息
Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA.
出版信息
Neuron. 2011 Dec 22;72(6):885-7. doi: 10.1016/j.neuron.2011.12.008.
PMID:22196322
Abstract
In this issue of Neuron, Malhotra and colleagues report an enrichment of de novo copy number variants in bipolar disorder and schizophrenia when compared with those of controls. The study highlights the importance of a genetic model involving rare and disruptive variants to further our understanding of complex neuropsychiatric traits.
摘要
在本期《神经元》杂志中，Malhotra 及其同事报道了与对照组相比，双相情感障碍和精神分裂症患者中新生拷贝数变异的富集。该研究强调了涉及罕见和破坏性变异的遗传模型对于深入了解复杂神经精神特征的重要性。
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