Hardie E M, Stone E A, Spaulding K A, Cullen J M
Department of Companion Animal and Special Species Medicine, College of Veterinary Medicine, North Carolina State University, Raleigh 27606.
Vet Surg. 1990 Sep-Oct;19(5):348-55. doi: 10.1111/j.1532-950x.1990.tb01205.x.
A technique was developed for subtotal prostatectomy in dogs with the neodymium:yttrium-aluminum-garnet (Nd:YAG) laser. In six normal dogs, full-thickness necrosis of the prostate occurred if the central-lateral region within 5 mm of the urethra was photoablated at 60 watts for 1 second. Moderate to superficial necrosis occurred when the prostate within 5 mm of the urethra was photoablated at 35 watts for 2 seconds or 60 watts for 0.5 second. At necropsy, leakage of the urethra occurred in two dogs at sites treated at 60 watts for 1 second. In a clinical study, complications associated with subtotal prostatectomy with the Nd:YAG laser (n = 6) were compared with complications associated with prostatic drainage (n = 6) in dogs with prostatic disease. Intraoperative death (2/6 dogs) and nocturnal incontinence (4/4 surviving dogs) occurred with subtotal prostatectomy. Uncontrolled prostatic infection (2/6 dogs) occurred with prostatic drainage and resulted in the death of one dog on day 11. Four of five dogs surviving prostatic drainage developed recurrent urinary tract infection.
开发了一种使用钕钇铝石榴石(Nd:YAG)激光对犬进行前列腺次全切除术的技术。在6只正常犬中,如果在距尿道5毫米范围内的中央外侧区域以60瓦功率照射1秒进行光凝,前列腺会发生全层坏死。当在距尿道5毫米范围内的前列腺以35瓦功率照射2秒或60瓦功率照射0.5秒进行光凝时,会发生中度至浅表坏死。尸检时,两只犬在以60瓦功率照射1秒的治疗部位出现尿道渗漏。在一项临床研究中,将患有前列腺疾病的犬接受Nd:YAG激光前列腺次全切除术(n = 6)的并发症与接受前列腺引流术(n = 6)的并发症进行了比较。前列腺次全切除术出现术中死亡(2/6只犬)和夜间尿失禁(4/4只存活犬)。前列腺引流术出现前列腺感染失控(2/6只犬),导致1只犬在第11天死亡。接受前列腺引流术存活的5只犬中有4只发生复发性尿路感染。