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在木糖醇用于成人龋齿试验(X-ACT)中,龋齿活跃的成年人的根龋存在和严重程度的风险指标。

Risk indicators for the presence and extent of root caries among caries-active adults enrolled in the Xylitol for Adult Caries Trial (X-ACT).

机构信息

University of North Carolina at Chapel Hill School of Dentistry, 433 Brauer Hall, CB#7450, Chapel Hill, NC 27599-7450, USA.

出版信息

Clin Oral Investig. 2012 Dec;16(6):1647-57. doi: 10.1007/s00784-011-0656-2. Epub 2011 Dec 24.

DOI:10.1007/s00784-011-0656-2
PMID:22198596
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11196008/
Abstract

OBJECTIVE

This paper uses baseline data from a randomized clinical trial to evaluate cross-sectional indicators of root caries in caries-active adults.

MATERIALS AND METHODS

Adults (21-80 years) having at least 12 erupted teeth and between one and ten caries lesions were enrolled. Participants (n = 437) received caries exams by trained, calibrated examiners and responded to baseline demographic and medical-dental questionnaires. We examined associations between baseline characteristics and (1) the presence of any root caries using Mantel-Haenszel hypothesis tests and odds ratio (OR) estimators and (2) the number of root surfaces with caries among study participants with exposed root surfaces (n = 349) using Mantel-Haenszel mean score tests and Mann-Whitney estimators.

RESULTS/CONCLUSIONS: Adjusting for study site and age, male gender [OR, 1.72; 95% confidence interval (CI), 1.08, 2.78], white race (OR, 2.39; 95% CI, 1.43, 3.98), recent dental visit (OR, 1.98; 95% CI, 1.07, 3.66), poor self-described oral health (OR, 2.65; 95% CI, 1.10, 6.39), and recent professional fluoride treatment (OR, 1.85; 95% CI, 1.06, 3.25) were significantly associated with increased odds to have any root caries, and study participants with exposed root surfaces characterized by male gender [Mann-Whitney probability estimate (MW) = 0.57; 95% CI, 0.51, 0.63), white race (MW, 0.61; 0.55, 0.68), recent dental visit (MW, 0.58; 0.50, 0.67), poor self-described oral health (MW, 0.61; 0.53, 0.69), and flossing at least once per day (MW, 0.57; 95% CI, 0.51, 0.62) were significantly more likely to have a greater number of root surfaces with caries than a randomly selected study participant from their respective complementary subgroups (female gender, non-white, etc.).

CLINICAL RELEVANCE

Our findings may help identify individuals at higher root caries risk.

摘要

目的

本研究使用一项随机临床试验的基线数据,评估活跃性龋成年人的根龋横断面指标。

材料和方法

纳入至少有 12 颗萌出牙且有 1 至 10 个龋损的 21-80 岁成年人。参与者(n=437)接受了经过培训和校准的检查者的龋病检查,并对基线人口统计学和医学-牙科问卷进行了回复。我们使用 Mantel-Haenszel 假设检验和比值比(OR)估计值,检查了基线特征与(1)任何根龋的存在之间的关联,以及(2)暴露根面的研究参与者中根面龋的数量之间的关联(n=349),使用 Mantel-Haenszel 平均得分检验和 Mann-Whitney 估计值。

结果/结论:在调整研究地点和年龄后,男性(OR,1.72;95%置信区间(CI),1.08,2.78)、白种人(OR,2.39;95%CI,1.43,3.98)、最近看牙(OR,1.98;95%CI,1.07,3.66)、自述口腔健康状况不佳(OR,2.65;95%CI,1.10,6.39)和最近接受专业氟化物治疗(OR,1.85;95%CI,1.06,3.25)与增加发生任何根龋的几率显著相关,且具有暴露根面特征的研究参与者为男性(Mann-Whitney 概率估计值(MW)=0.57;95%CI,0.51,0.63)、白种人(MW,0.61;95%CI,0.55,0.68)、最近看牙(MW,0.58;95%CI,0.50,0.67)、自述口腔健康状况不佳(MW,0.61;95%CI,0.53,0.69)和每天至少用牙线洁牙一次(MW,0.57;95%CI,0.51,0.62),与各自互补亚组中随机选择的研究参与者相比,他们更有可能有更多的根面发生龋病。

临床相关性

我们的研究结果可能有助于识别更高根龋风险的个体。

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本文引用的文献

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J Public Health Dent. 2011 Fall;71(4):335-44. doi: 10.1111/j.1752-7325.2011.00278.x. Epub 2011 Aug 17.
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Design of the xylitol for adult caries trial (X-ACT).木糖醇用于成人龋齿试验(X-ACT)的设计。
BMC Oral Health. 2010 Sep 29;10:22. doi: 10.1186/1472-6831-10-22.
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