Crocombe L A, Brennan D S, Slade G D, Stewart J F, Spencer A J
Australian Research Centre for Population Oral Health, School of Dentistry, The University of Adelaide, Adelaide, South Australia, Australia; Centre for Rural Health, The University of Tasmania, Hobart, Tasmania, Australia.
Aust Dent J. 2015 Mar;60(1):30-7. doi: 10.1111/adj.12243.
The aim of this study was to confirm whether the level of lifetime fluoridation exposure is associated with lower dental caries experience in younger adults (15-46 years).
Data of the cohort born between 1960 and 1990 residing outside Australia's capital cities from the 2004-2006 Australian National Survey of Adult Oral Health were analysed. Residential history questionnaires were used to determine the percentage of each person's lifetime exposure to fluoridated water (<50%/50+%). Examiners recorded decayed, missing and filled permanent teeth (DMFT). Socio-demographic variables, periodontal risk factors, and access to dental care were included in multivariable least-squares regression models.
In bivariate analysis, the higher level of fluoridation category had significantly lower DMFT (mean 6.01 [SE=0.62]) than the lower level of fluoridation group (9.14 [SE=0.73] p<0.01) and lower numbers of filled teeth (4.08 [SE=0.43], 7.06 [SE=0.62], p<0.01). In multivariate analysis, the higher number of full-time equivalent dentists per 100,000 people was associated with a lower mean number of missing teeth (regression coefficient estimate=-1.75, p=0.03), and the higher level of water fluoridation with a lower mean DMFT (-2.45, p<0.01) and mean number of filled teeth (-2.52, p<0.01).
The higher level of lifetime fluoridation exposure was associated with substantially lower caries experience in younger rural adults, largely due to a lower number of filled teeth.
本研究旨在确认终生氟暴露水平是否与年轻成年人（15 - 46岁）较低的龋齿经历相关。
分析了2004 - 2006年澳大利亚全国成人口腔健康调查中出生于1960年至1990年、居住在澳大利亚首府城市以外地区的队列数据。使用居住史问卷来确定每个人终生暴露于含氟水的百分比（<50%/50%及以上）。检查人员记录恒牙的龋、失、补牙数（DMFT）。社会人口统计学变量、牙周危险因素和获得牙科护理的情况被纳入多变量最小二乘回归模型。
在双变量分析中，较高氟暴露类别组的DMFT（均值6.01 [标准误 = 0.62]）显著低于较低氟暴露组（9.14 [标准误 = 0.73]，p<0.01），补牙数也较少（4.08 [标准误 = 0.43]，7.06 [标准误 = 0.62]，p<0.01）。在多变量分析中，每10万人中全职等效牙医数量较多与平均缺牙数较低相关（回归系数估计值 = -1.75，p = 0.03），而较高的水氟暴露水平与较低的平均DMFT（-2.45，p<0.01）和平均补牙数（-2.52，p<0.01）相关。
终生较高的氟暴露水平与年轻农村成年人较低的龋齿经历显著相关，主要原因是补牙数较少。
