Alghamdi Khalid M, Khurram Huma, Taïeb Alain
Department of Dermatology, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Indian J Dermatol Venereol Leprol. 2012 Jan-Feb;78(1):74-81. doi: 10.4103/0378-6323.90950.
The details of phototherapy practices for vitiligo have been rarely studied.
To explore the details of phototherapy practices for vitiligo among dermatologists.
A self-administered questionnaire about the details of phototherapy practices for vitiligo was distributed to all dermatologists attending a national general dermatology conference in Riyadh, Saudi Arabia, in 2008.
Questionnaires were returned by 121 of 140 participants (response rate = 86.4%). The mean age of the respondents was 39.34 ± 9.7 years, and 65% were males. One hundred eight of 110 (98.2%) respondents provided phototherapy to their vitiligo patients. The mean number of vitiligo patients who underwent phototherapy each week per dermatologist's office was 18 ± 2.26. Narrowband ultraviolet B (NB-UVB) was the most common modality chosen to treat generalized vitiligo (84%). Excimer laser was the most common modality used to treat focal and segmental vitiligo (53% and 39%, respectively). Sixty-eight percent of dermatologists administered a fixed starting dose of NB-UVB to all patients, whereas 31% used the minimal erythema dose as a guide. Fifty percent reported that NB-UVB resulted in better color matching with the surrounding skin. Thirty-seven percent favored NB-UVB over psoralen + ultraviolet A for a faster response, and 31% preferred NB-UVB for a pigmentation that is more durable. Forty-seven percent (50/106) of the respondents limited the number of phototherapy sessions to reduce the risks of skin cancer. However, no respondent reported any skin cancer incidence in phototherapy-treated vitiligo patients.
There is a need for phototherapy guidelines for the treatment of vitiligo in patients with skin of color.
白癜风光疗实践的细节鲜有研究。
探讨皮肤科医生对白癜风进行光疗实践的细节。
2008年，向参加沙特阿拉伯利雅得全国普通皮肤病学会议的所有皮肤科医生发放了一份关于白癜风光疗实践细节的自填式问卷。
140名参与者中有121人返回了问卷（回复率 = 86.4%）。受访者的平均年龄为39.34 ± 9.7岁，65%为男性。110名受访者中有108人（98.2%）为白癜风患者提供光疗。每位皮肤科医生办公室每周接受光疗的白癜风患者平均人数为18 ± 2.26人。窄谱中波紫外线（NB-UVB）是治疗泛发性白癜风最常用的方法（84%）。准分子激光是治疗局限性和节段性白癜风最常用的方法（分别为53%和39%）。68%的皮肤科医生给所有患者使用固定起始剂量的NB-UVB，而31%以最小红斑量为指导。50%的人报告说NB-UVB能使皮肤颜色与周围皮肤更好地匹配。37%的人认为NB-UVB比补骨脂素 + 紫外线A反应更快，31%的人更喜欢NB-UVB，因为其色素沉着更持久。47%（50/106）的受访者限制光疗次数以降低皮肤癌风险。然而，没有受访者报告光疗治疗的白癜风患者中有任何皮肤癌发生。
需要针对有色人种皮肤白癜风患者的光疗指南。
