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(4aS,4bR,7R,10aS)-3,7-二甲基-10a-(丙烷-2-基)-1,4,4a,4b,5,6,7,8,10,10a-十氢菲-1,4-二酮

(4aS,4bR,7R,10aS)-3,7-Dimethyl-10a-(propan-2-yl)-1,4,4a,4b,5,6,7,8,10,10a-deca-hydro-phenanthrene-1,4-dione.

作者信息

Caracelli Ignez, Zukerman-Schpector Julio, Machado André T Lousada, Brocksom Timothy J, Ferreira M Lúcia, Tiekink Edward R T

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 Dec 1;67(Pt 12):o3192. doi: 10.1107/S160053681104517X. Epub 2011 Nov 5.

DOI:10.1107/S160053681104517X
PMID:22199712
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3238859/
Abstract

In the title compound, C(19)H(26)O(2), the A ring adopts a chair conformation, whereas the B and C rings both adopt distorted half-chair conformations with the quaternary C atom common to both rings lying 0.577 (3) and 0.648 (3) Å out of the approximate plane defined by the remaining five C atoms (r.m.s. deviations = 0.1386 and 0.1156 Å) for the B and C rings, respectively. Mol-ecules are assembled in the crystal through C-H⋯O inter-actions involving both carbonyl O atoms, which lead to supra-molecular chains aligned along the b axis.

摘要

在标题化合物C(19)H(26)O(2)中，A环呈椅式构象，而B环和C环均呈扭曲的半椅式构象，两个环共有的季碳原子分别偏离由其余五个碳原子定义的近似平面0.577 (3) Å和0.648 (3) Å（B环和C环的均方根偏差分别为0.1386 Å和0.1156 Å）。分子在晶体中通过涉及两个羰基O原子的C—H⋯O相互作用组装，形成沿b轴排列的超分子链。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/177b/3238859/0ac681e46b41/e-67-o3192-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/177b/3238859/daef1b3712ec/e-67-o3192-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/177b/3238859/d90a9f3fef3a/e-67-o3192-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/177b/3238859/0ac681e46b41/e-67-o3192-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/177b/3238859/daef1b3712ec/e-67-o3192-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/177b/3238859/d90a9f3fef3a/e-67-o3192-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/177b/3238859/0ac681e46b41/e-67-o3192-fig3.jpg

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本文引用的文献

1
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2
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Planta Med. 2011 Sep;77(14):1594-6. doi: 10.1055/s-0030-1270933. Epub 2011 Mar 16.
3
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.