• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

(4R*,4aS*,4bS*,5R*,10aR*)-4-羟基-4a,5-二甲基-2-(丙烷-2-基)-1,4,4a,4b,5,6,7,8,10,10a-十氢菲-1-酮

(4R*,4aS*,4bS*,5R*,10aR*)-4-Hy-droxy-4a,5-dimethyl-2-(propan-2-yl)-1,4,4a,4b,5,6,7,8,10,10a-deca-hydro-phenan-thren-1-one.

作者信息

Caracelli Ignez, Zukerman-Schpector Julio, Machado André T Lousada, Brocksom Timothy J, Ferreira M Lúcia, Tiekink Edward R T

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 Dec 1;67(Pt 12):o3338. doi: 10.1107/S1600536811048008. Epub 2011 Nov 16.

DOI:10.1107/S1600536811048008
PMID:22199834
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3238985/
Abstract

In the title compound, C(19)H(28)O(2), the A ring adopts a chair conformation. Both the B and C rings adopt envelope conformations with the C atoms common to both rings and adjacent to the carbonyl and hydroxyl groups, respectively, lying 0.604 (3) and 0.634 (3) Å out of the mean planes defined by the remaining five C atoms of rings B and C, respectively (r.m.s. deviations = 0.0100 and 0.0157 Å, respectively). The formation of linear supra-molecular C(7) chains along the a axis mediated by hy-droxy-O-H⋯O(carbon-yl) hydrogen bonds is the most prominent feature of the crystal packing.

摘要

在标题化合物C(19)H(28)O(2)中，A环呈椅式构象。B环和C环均呈信封式构象，两个环共有的且分别与羰基和羟基相邻的C原子，相对于由环B和环C其余五个C原子所定义的平均平面，分别偏离0.604 (3) Å和0.634 (3) Å（均方根偏差分别为0.0100 Å和0.0157 Å）。由羟基O—H⋯O(羰基)氢键介导沿a轴形成线性超分子C(7)链是晶体堆积的最显著特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/3238985/ed179602373f/e-67-o3338-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/3238985/425ddea5a3f5/e-67-o3338-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/3238985/f58e36cb8b6a/e-67-o3338-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/3238985/ed179602373f/e-67-o3338-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/3238985/425ddea5a3f5/e-67-o3338-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/3238985/f58e36cb8b6a/e-67-o3338-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/3238985/ed179602373f/e-67-o3338-fig3.jpg

相似文献

1
(4R*,4aS*,4bS*,5R*,10aR*)-4-Hy-droxy-4a,5-dimethyl-2-(propan-2-yl)-1,4,4a,4b,5,6,7,8,10,10a-deca-hydro-phenan-thren-1-one.(4R*,4aS*,4bS*,5R*,10aR*)-4-羟基-4a,5-二甲基-2-(丙烷-2-基)-1,4,4a,4b,5,6,7,8,10,10a-十氢菲-1-酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Dec 1;67(Pt 12):o3338. doi: 10.1107/S1600536811048008. Epub 2011 Nov 16.
2
(4R,4aS,4bS,7R,10aR)-4-Hy-droxy-4a,7-dimethyl-2-(propan-2-yl)-1,4,4a,4b,5,6,7,8,10,10a-deca-hydro-phenanthren-1-one.(4R,4aS,4bS,7R,10aR)-4-羟基-4a,7-二甲基-2-(丙烷-2-基)-1,4,4a,4b,5,6,7,8,10,10a-十氢菲-1-酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Nov;67(Pt 11):o3136. doi: 10.1107/S1600536811044540. Epub 2011 Oct 29.
3
(4aS,4bR,7R,10aS)-3,7-Dimethyl-10a-(propan-2-yl)-1,4,4a,4b,5,6,7,8,10,10a-deca-hydro-phenanthrene-1,4-dione.(4aS,4bR,7R,10aS)-3,7-二甲基-10a-(丙烷-2-基)-1,4,4a,4b,5,6,7,8,10,10a-十氢菲-1,4-二酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Dec 1;67(Pt 12):o3192. doi: 10.1107/S160053681104517X. Epub 2011 Nov 5.
4
3-Hy-droxy-2-[(2-hy-droxy-4,4-dimethyl-6-oxocyclo-hex-1-en-1-yl)(3-nitro-phen-yl)meth-yl]-5,5-dimethyl-cyclo-hex-2-en-1-one.3-羟基-2-[(2-羟基-4,4-二甲基-6-氧代环己-1-烯-1-基)(3-硝基苯基)甲基]-5,5-二甲基环己-2-烯-1-酮
Acta Crystallogr Sect E Struct Rep Online. 2010 Oct 13;66(Pt 11):o2806-7. doi: 10.1107/S1600536810040079.
5
(1R,4aS,10aR)-1,4a-Dimethyl-N-[(morpholin-4-yl)carbothio-yl]-7-(propan-2-yl)-1,2,3,4,4a,9,10,10a-octa-hydro-phenanthrene-1-carboxamide.（1R，4aS，10aR）-1，4a-二甲基-N-[(吗啉-4-基)碳硫酰基]-7-(丙烷-2-基)-1，2，3，4，4a，9，10，10a-八氢菲-1-甲酰胺
Acta Crystallogr Sect E Struct Rep Online. 2010 Nov 6;66(Pt 12):o3079-80. doi: 10.1107/S1600536810044569.
6
7-Deacetyl-gedunin.7-脱乙酰基格杜宁
Acta Crystallogr Sect E Struct Rep Online. 2010 Dec 18;67(Pt 1):o158-9. doi: 10.1107/S1600536810052037.
7
Corymbolone.棒曲霉素
Acta Crystallogr Sect E Struct Rep Online. 2014 Jun 11;70(Pt 7):o758. doi: 10.1107/S1600536814012938. eCollection 2014 Jul 1.
8
2-[(8-Meth-oxy-carbonyl-4b,8-dimethyl-4b,5,6,7,8,8a,9,10-octa-hydro-phenan-thren-3-yl)amino]-3,5-dinitro-benzoic acid ethyl acetate monosolvate.2-[(8-甲氧基羰基-4b,8-二甲基-4b,5,6,7,8,8a,9,10-八氢菲-3-基)氨基]-3,5-二硝基苯甲酸乙酸乙酯单溶剂合物
Acta Crystallogr Sect E Struct Rep Online. 2012 Sep 1;68(Pt 9):o2674. doi: 10.1107/S1600536812032278. Epub 2012 Aug 11.
9
N,N-Di-methyl-dehydro-abietyl-ammonium chloride ethanol monosolvate.N,N-二甲基脱氢枞基氯化铵乙醇单溶剂合物
Acta Crystallogr Sect E Struct Rep Online. 2013 May 25;69(Pt 6):o959. doi: 10.1107/S1600536813013846. Print 2013 Jun 1.
10
Crystal structure of 16-hy-droxy-4,4,10,13,14-penta-methyl-17-(6-methyl-hept-5-en-2-yl)-4,5,6,9,10,11,12,13,14,15,16,17-dodeca-hydro-1H-cyclo-penta-[a]phenanthren-3(2H)-one.16-羟基-4,4,10,13,14-五甲基-17-(6-甲基庚-5-烯-2-基)-4,5,6,9,10,11,12,13,14,15,16,17-十二氢-1H-环戊并[a]菲-3(2H)-酮的晶体结构
Acta Crystallogr E Crystallogr Commun. 2015 Jun 13;71(Pt 7):o464-5. doi: 10.1107/S2056989015010592. eCollection 2015 Jul 1.

本文引用的文献

1
neo-Clerodane diterpenes from Ajuga ciliata Bunge and their neuroprotective activities.中华荆芥中的新 clerodane 二萜及其神经保护活性。
Fitoterapia. 2011 Oct;82(7):1123-7. doi: 10.1016/j.fitote.2011.07.010. Epub 2011 Jul 23.
2
Antiplasmodial and antitrypanosomal activity of tanshinone-type diterpenoids from Salvia miltiorrhiza.丹参酮型二萜类化合物的抗疟原虫和抗锥虫活性。
Planta Med. 2011 Sep;77(14):1594-6. doi: 10.1055/s-0030-1270933. Epub 2011 Mar 16.
3
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.