Kose Muhammet, McKee Vickie
Department of Chemistry, Loughborough University, Loughborough LE11 3TU, England.
Acta Crystallogr Sect E Struct Rep Online. 2011 Dec 1;67(Pt 12):o3193. doi: 10.1107/S1600536811045399. Epub 2011 Nov 5.
The title compound, 2C(21)H(19)N(3)O(2)·H(2)O, was synthesized by a Schiff base condensation of 2,6-diformyl-pyridine with 2-amino-4-methyl-phenol in ethanol. In the crystal, two mol-ecules of 2,6-bis-[(2-hy-droxy-5-methyl-phen-yl)imino-meth-yl]pyridine dimer-ize via hydrogen bonding to a water mol-ecule, which lies on a twofold axis. There are also intra-molecular phenol-imine hydrogen bonds. The dimers are further linked via π-π (phen-yl-pyridine) [centroid-centroid distance = 3.707 (2) Å] and π-π edge-to-edge [3.392 (2) Å] inter-actions. The dihedral angles between the central ring and the two pendant rings are 11.46 (8) and 2.06 (8)° while the pendant rings make a dihedral angle of 10.14 (8)°.
标题化合物2C(21)H(19)N(3)O(2)·H(2)O是通过2,6 - 二甲基吡啶与2 - 氨基 - 4 - 甲基苯酚在乙醇中进行席夫碱缩合反应合成的。在晶体中，两个2,6 - 双[（2 - 羟基 - 5 - 甲基苯基）亚氨基甲基]吡啶分子通过氢键与位于二重轴上的一个水分子二聚。还存在分子内酚 - 亚胺氢键。这些二聚体通过π - π（苯基 - 吡啶）[质心 - 质心距离 = 3.707 (2) Å]和π - π边对边[3.392 (2) Å]相互作用进一步连接。中心环与两个侧环之间的二面角分别为11.46 (8)°和2.06 (8)°，而侧环之间的二面角为10.14 (8)°。
